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Epidural Anesthesia clinical trials

View clinical trials related to Epidural Anesthesia.

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NCT ID: NCT06316921 Completed - Pain, Postoperative Clinical Trials

Epidural PCA on Pain Relief After L-spine Surgery

Start date: June 1, 2021
Phase:
Study type: Observational

This study aimed to evaluate the effect of epidural patient-controlled analgesia (PCA) on postoperative pain relief after lumbar spine surgeries. The eligible patients received two types of postoperative pain management: PCA and standard pain treatment. Comparisons between the two groups were made in terms of postoperative pain level.

NCT ID: NCT06069219 Completed - Abdominal Surgery Clinical Trials

Pharmacokinetics of Sufentanil After Epidural Administration

Start date: June 1, 2019
Phase:
Study type: Observational

Sufentanil is an opioid analgesics used in all groups of patients. It has one of the strongest effects among analgesic drugs. Sufentanil is widely-used because of its very quick onset, short duration of action, and better hemodynamic stability in patients compared to other opioids. Most of the pharmacokinetic studies described intravenous administration of sufentanil. The drug can also be epidural administrated (especially continuous epidural infusion) in low concentration with local anesthetics (ropivacaine or bupivacaine) for epidural analgesia. Epidural analgesia offers effective pain relief not only during the surgery, but also postoperatively. The combination of two drugs provides their additive effect and can reduce doses required for pain relief, then decreases the number and severity of adverse events. The study aims to describe the pharmacokinetics of epidural sufentanil used perioperative in adult patients after abdominal surgery to adjust the dosage if necessary.

NCT ID: NCT05557383 Completed - Labor Clinical Trials

Effect of Using Peanut Ball on the Length of Labor for Women Laboring With an Epidural

peanutball
Start date: October 24, 2019
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate the Effect of using peanut ball on the length of labor, delivery pattern and childbirth satisfaction for women laboring with an Epidural.This study aims to understand the intervention of using peanut ball in the future during the delivery period is expected.it is expected to reduce the cesarean section with delayed delivery.

NCT ID: NCT05344079 Completed - Epidural Anesthesia Clinical Trials

Comparison of the Effects of Epidural Analgesia and Local Infiltrative Analgesia Methods on Pain Control

Start date: May 1, 2016
Phase: N/A
Study type: Interventional

Total knee arthroplasty (TKA) is one of the major orthopedic surgeries that cause severe postoperative pain. 60% of the patients undergoing TKA have severe pain and 30% have moderate pain postoperatively. Many methods are used in the effective treatment of pain after TKA. The administration of analgesic drugs to the wound site in the form of local infiltration is included in the pain treatment both as an independent technique and in addition to multimodal analgesia in the treatment of postoperative pain. Epidural analgesia (EA) is known for its place in the treatment of pain after TKA and its suppressive effect on the stress response. Similar to the study, no publication was found in the literature that evaluated the suppression of surgical stress response and the effectiveness of local infiltrative analgesia (LIA) in lower extremity surgery. Therefore, it was aimed in the study to compare the effects of EA and LIA on postoperative pain and stress response in patients who underwent total knee arthroplasty.

NCT ID: NCT05327088 Completed - Labor Pain Clinical Trials

Epidural Dexmedetomidine vs Nalbuphine for Labor Analgesia

Start date: September 12, 2021
Phase: Phase 2
Study type: Interventional

The aim of this study is to compare epidural dexmedetomidine vs nalbuphine added to bupivacaine in labor analgesia and determine the privilege of one over the other and to compare the effect of both analgesics after delivery.

NCT ID: NCT04721054 Completed - General Anesthesia Clinical Trials

Thoracic Epidural Versus General Anesthesia for Laparoscopic Cholecystectomy

Start date: October 1, 2018
Phase: N/A
Study type: Interventional

Eighty two patients planned to undergo elective laparoscopic cholecystectomy were divided into two groups, T and G, randomly. In Group T all patients underwent laparoscopic cholecystectomy under thoracic epidural anesthesia with 12mlof 0.25% bupivacaine and 1% lignocaine plain whereas in group G all patients underwent surgery under general anesthesia. Intra-operative heart rate, mean arterial pressure (MAP) and post operative opioid consumption in first 24hrs were recorded as primary outcomes whereas presence or absence of respiratory complication and duration of hospital stay as secondary outcome.

NCT ID: NCT04373174 Completed - Thoracic Surgery Clinical Trials

The Effect of Regional Anesthesia Techniques on Brain Tissue Oxygenation in Thoracic Surgery

Start date: May 1, 2020
Phase: N/A
Study type: Interventional

Today, it is preferred that the lung with pathology for thorax surgery is not under ventilation during operation in terms of reliability and ease of operation. For this reason, the anesthesia approach is characteristic and it is ensured that the single lung is not ventilated during the operation by means of specially manufactured intubation tubes. This application can disrupt tissue oxygenation due to both Operation position and single lung ventilation. Thoracic epidural analgesia, which is applied as the gold standard of Thoracic Surgery, is applied prior to the operation and is provided to assist in postoperative analgesia.

NCT ID: NCT04352283 Completed - Clinical trials for Epidural; Anesthesia

Does Ultrasound Increase the First-pass Success of Epidural Space Identification in Obese Parturients

Start date: April 6, 2019
Phase: N/A
Study type: Interventional

Obesity is associated with difficulties in epidural space catheterization. The investigators want to prove that a pre-procedural ultrasound exam of lumbar spine increase the first-pass success rate of the epidural space identification among obese parturients.

NCT ID: NCT04222192 Completed - Ultrasound Clinical Trials

Different Type Ultrasound Guided Epidural Block Methods

Start date: January 15, 2020
Phase: N/A
Study type: Interventional

The nerve blocks applied with ultrasonography are used for pain and operation after many operations today. Applications with ultrasonography shorten the processing time, reduce the amount of local anesthetic used and lead to fewer complications. However, the use of ultrasonography is not so common in neuraxial regional anesthesia applications. In the literature, epidural applications accompanied by ultrasonography were applied with different approaches.

NCT ID: NCT03721432 Completed - Epidural Anesthesia Clinical Trials

The Effect of Oral Pregabalin on Epidural-induced Shivering and Epidural Characteristics

Start date: May 20, 2018
Phase: N/A
Study type: Interventional

- Background: The previous reports tried to reduce shivering and improve neuroaxial anesthesia characteristics by the systemic use of different drugs. This study was directed to evaluate the effect of pregabalin premedication on both shivering and epidural outcome data following single shot loading. - Patients and Methods: Eighty patients, ASA grade I and II, undergoing surgeries under epidural anesthesia were studied. The patients were divided into two groups: Pregabalin group and Control group in which the patients received 150 mg of pregabalin and placebo capsules respectively sixty minutes prior to surgery. Following epidural loading, the onset and degree of shivering were compared between the two groups. Also, the epidural outcome including onset, level and duration were traced and compared. The perioperative hemodynamics, sedation scores, patient satisfaction and side effects were followed up and registered.