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Enuresis clinical trials

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NCT ID: NCT03098992 Active, not recruiting - Clinical trials for Stress Urinary Incontinence

The Efficacy and Safety of Fotona Smooth® Device for the Treatment of Stress Urinary Incontinence

Start date: June 1, 2017
Phase: N/A
Study type: Interventional

There are many existing treatments of female stress urinary incontinence such as the use of adult absorbent pads and diapers, behavioral training, including bladder training, pelvic muscle exercises, biofeedback, urethral plugs, intravaginal prosthesis, electrical stimulation, periurethral injections, and reconstructive surgery. However, there is still a lack of effective minimally invasive treatment options that are independent of patient compliance. One emerging approach of minimally invasive SUI therapy is pelvic floor reinforcement using laser therapy. The primary objective of this post-marketing study is to confirm the effectiveness and safety of the FotonaSmooth® device in the treatment of stress urinary incontinence (SUI) in a large number of females using objective and subjective methods. Patients with stress incontinence will be assigned to two groups, an active group, where the Fotona Dynamis Er:YAG Laser System will be used, and a sham group where a very low laser setting will be used, and parameter presentations will be masked. Participants will be adult females, 18 years old and older with clinical and urodynamic diagnosis of Stress Urinary Incontinence,who have had no significant improvement in urinary incontinence from at least one previous conservative treatment, such as behavioral measures, pelvic floor muscle training or the use of absorbent pads

NCT ID: NCT03052985 Active, not recruiting - Clinical trials for Pelvic Organ Prolapse

Materiovigilance After Urinary Incontinence or Prolapse Surgery

VIGI-MESH
Start date: February 14, 2017
Phase:
Study type: Observational [Patient Registry]

Observatory of Materiovigilance After Surgery of Urinary Incontinence or Prolapse in Women Implantable medical devices (meshes) used in pelvic organ prolapse surgery (genital prolapse, rectal prolapse), or incontinence surgery may be source of severe complications.

NCT ID: NCT02983461 Active, not recruiting - Clinical trials for Urinary Incontinence

Use of Sildenafil for Treatment of Urinary Incontinence

Start date: March 10, 2017
Phase: Phase 1
Study type: Interventional

The investigators goal is to develop medical treatments for stress/mixed urinary incontinence. Sildenafil has been shown to improve blood flow as well as muscle mass and strength and to decrease muscle fatigue. The investigators believe that it will improve muscular atrophy in the pelvic floor, thus improving symptoms of urinary incontinence related to pelvic floor dysfunction.

NCT ID: NCT02757274 Active, not recruiting - Clinical trials for Urinary Incontinence, Stress

Prospective Registry for Patients Undergoing Surgery for Male Stress Urinary Incontinence

SATURN
Start date: February 22, 2017
Phase:
Study type: Observational [Patient Registry]

This will be a prospective collection of pre-defined parameters on the treatment of male stress urinary incontinence by an artificial urinary sphincter (AUS) and male sling. The data collection will be undertaken from multiple centers in Europe. The participation will be by open invitation to all members of the Female & Functional Section of the EAU (ESFFU) along with other urologists undertaking these procedures. There will be a call via the European Association of urology (EAU) to all European Urologists to register for database entry. There will be no restriction on the number of patients enrolled as long as they are consecutive. The aim is to have a long term collection of the data set from as many centers as possible. An initial assessment for the robustness of the data collection will be undertaken at 3 months by a nominated steering committee. However, the first clinical evaluation of the data collected will commence at 1 year by the steering committee. Thereafter, the evaluations will be performed after every 2 years.

NCT ID: NCT02667431 Active, not recruiting - Endometrial Cancer Clinical Trials

Cancer of the Uterus and Treatment of Stress Urinary Incontinence

CUTI
Start date: January 2016
Phase:
Study type: Observational

Concurrent treatment of endometrial cancer and SUI may improve QOL, emotional and physical health and decrease costs for both patients and the health care system. At the time of endometrial cancer diagnosis, not only are women evaluated by a gynecologist and/or a gynecologic oncologist, but the majority will undergo surgery within weeks of their diagnosis. Thus, urinary incontinence could easily be identified, a referral made, and concurrent surgery performed. This would spare the patient two surgeries, decrease the emotional distress associated with SUI symptoms, decrease the costs associated with SUI for the patient and possibly improve overall quality of life. The proposed study will compare the quality of life and clinical outcomes among women with endometrial cancer and SUI that have concurrent surgery to women that do not have concurrent surgery. The findings of our proposed research will provide valuable information necessary for woman and clinicians to make decisions regarding the treatment of SUI, including evidence regarding the risks and benefits of performing concurrent endometrial cancer and SUI surgery.

NCT ID: NCT02538991 Active, not recruiting - Clinical trials for Urinary Stress Incontinence

TVT Versus Bulkamid®-Injections in Treatment of Stress Urinary Incontinence

Start date: September 2015
Phase: N/A
Study type: Interventional

One out of three adult females suffer from daily urinary incontinence. Two thirds of urinary incontinence is physical activity-related stress urinary incontinence (SUI). If the first-line treatment for SUI, training of pelvic floor muscles, is insufficient, treatment options are suburethral sling operation or transurethral bulking injection. Randomized studies between TVT and Bulkamid® and the knowledge about cost-effectiveness and patient satisfaction is missing. This prospective randomized study compares TVT and Bulkamid®-injections in treatment of SUI. Main outcome measures are patient satisfaction, complications and effectiveness of the treatment in reducing urinary leakage. Secondary outcome measures are cost-effectiveness, pain during and after treatment and changes in Quality of Life and symptoms.

NCT ID: NCT02446808 Active, not recruiting - Clinical trials for Urinary Incontinence

Intraoperative Nerve Monitoring During Robot-assisted Laparoscopic Prostatectomy

Start date: June 2015
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether the use of intraoperative nerve monitoring during robotic-assisted laparoscopic prostatectomy surgery improves post-surgery urinary continence and erectile function.

NCT ID: NCT02318251 Active, not recruiting - Clinical trials for Urinary Incontinence, Stress

Stress Urinary Incontinence Physiotherapy

Start date: January 2015
Phase: N/A
Study type: Interventional

The purpose of the present study is to compare two different physiotherapy programs regarding their effect on stress urinary incontinence.

NCT ID: NCT02039830 Active, not recruiting - Clinical trials for Urinary Incontinence

Group Versus Individual Physiotherapy for Urinary Incontinence in Aging Women

GROUP
Start date: July 2012
Phase: N/A
Study type: Interventional

The recommended treatment for urinary incontinence (UI) in women is individualised pelvic floor muscle (PFM) training, a costly and resource-intense approach; one Canada is currently unable to meet. This non-inferiority randomized control trial seeks to determine if group-based PFM training is as effective as individualised PFM training for treating UI in women 65 and over, and to establish the cost-effectiveness of both. Demonstrating that group-based treatment is at least as good as individualised one-on-one treatment and more cost-effective would warrant including group-based PFM training as a first-line UI treatment.

NCT ID: NCT01582542 Active, not recruiting - Nocturnal Enuresis Clinical Trials

Desmopressin for Improving Nocturnal Enuresis in Patients After Radical Cystectomy With Bladder Reconstruction

Start date: April 2012
Phase: Phase 4
Study type: Interventional

The purpose of this study is to prospectively assess whether Desmopressin, given for a period of month to patients after radical cystectomy with orthotopic bladder reconstruction, improves and lowers the rate of nocturnal enuresis.