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Enuresis clinical trials

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NCT ID: NCT03877432 Active, not recruiting - Clinical trials for Spinal Cord Injuries

Non-invasive Nerve Stimulation for Inhibition of Bladder Incontinence in Spinal Cord Injured Subjects.

Start date: October 21, 2016
Phase: N/A
Study type: Interventional

Investigators will test S2-S4 dermatome stimulation with spinal cord injury (SCI) individuals using intermittent catheterization to estimate the clinical impact on bladder capacity and continence. For individuals with SCI using intermittent catheterization, investigators hypothesize that dermatome stimulation will decrease bladder spasm frequency and intensity, and reduce bladder incontinence chronically. The goal of this study is to provide objective evidence for the assertion that dermatome stimulation chronically decreases bladder activity and therefore the unwanted side effects of neurogenic bladder. This project will improve the understanding of the neurophysiology of afferent-mediated neural pathways that affect bladder function, and translate recent advances discovered in animal and human studies into clinical research and treatment. The ability to void safely and effectively by electrical stimulation without cutting sacral nerves or the external urethral sphincter would be a major advance. A socially acceptable, predictable and reliable device for reducing incontinence would be widely used and improve quality of life.

NCT ID: NCT03681678 Active, not recruiting - Clinical trials for Urinary Incontinence

Laser Therapy for Treatment of Urogenital Symptoms in Women

Start date: October 8, 2018
Phase:
Study type: Observational [Patient Registry]

This is a prospective observational study of women undergoing vaginal treatment with the fractional carbon dioxide (fCO2) laser for various urogenital symptoms.

NCT ID: NCT03671694 Active, not recruiting - Clinical trials for Stress Urinary Incontinence

Laser Vaginal Treatment for SUI

Start date: September 19, 2018
Phase: N/A
Study type: Interventional

RCT designed to answer the question: Does the application of Erbium: YAG laser treatment to the vagina improve urine control for women with SUI?

NCT ID: NCT03620604 Active, not recruiting - Clinical trials for Urinary Incontinence,Stress

Mid Term Safety and Efficacy of ALTIS® Single Incision Sling for Female Stress Urinary Incontinence (SUI).

Start date: January 1, 2014
Phase:
Study type: Observational [Patient Registry]

Prospective, single-arm, non-sponsored, observational single centre trial in a cohort of patients undergoing stress urinary incontinence surgery with ALTIS® procedure. All patients were diagnosed according to clinical reports, physical exploration and urodynamics. Body mass index(BMI) was categorized according to World Health Organization classification. Valsalva leak point pressure was categorized in three groups <60 cmH2O, 60-90 cmH2O and >90 cmH2O). Participants were evaluated post-operatively at 1, 6, 12 and 24 months with physical examination, ICIQ-SF, visual scale of satisfaction(SVS)(0-10). Adverse events were reported in each visit. Multivariate analysis for risk factors of surgery failure was performed.

NCT ID: NCT03556891 Active, not recruiting - Overactive Bladder Clinical Trials

Pivotal Study of eCoin for Overactive Bladder With Urgency Urinary Incontinence

Start date: September 4, 2018
Phase: N/A
Study type: Interventional

This trial is a prospective, multicenter, single-arm study of the safety and effectiveness of eCoinTM tibial nerve stimulation in subjects having overactive bladder (OAB) with urgency urinary incontinence (UUI). The study will evaluate changes from baseline in OAB symptoms as measured by voiding diaries and patient reported-outcomes through 48 weeks of eCoinTM therapy or 52 weeks of implantation.

NCT ID: NCT03474653 Active, not recruiting - Clinical trials for Urinary Incontinence

LATITUDE An Observational Study of Patient Choice and the Urethral Bulking Agent, Bulkamid®

Start date: June 12, 2017
Phase:
Study type: Observational

Latitude is an observational study exploring how effective Bulkamid ® is as a first line treatment for women with stress urinary incontinence. Women who choose to have Bulkamid as part of their standard clinical care will be asked to complete questionnaires before and after their surgery so that we can assess how their urinary symptoms change. As a second part of the study, we are asking all patients having any first line treatment for stress incontinence to complete a short questionnaire telling us how they decided what treatment to have. A small number of these women will be contacted via telephone and asked whether they would mind being interviewed to tell us more about this. We will also interview a number of doctors taking part in Latitude to find out how they counsel patients about different treatment options for stress urinary incontinence.

NCT ID: NCT03468465 Active, not recruiting - Clinical trials for Urinary Incontinence

Peripheral Transcutaneous Neuromodulation of the Post-tibial Nerve for Solifenacin 10 mg. Hyperactive Bladder Syndrome

SOLITENS
Start date: May 4, 2018
Phase: Phase 4
Study type: Interventional

- To determine if the T-PTNS is not inferior in the short term (3 months) to one of the usual pharmacological treatments (Solifenacin) in the treatment of hyperactive bladder syndrome and with respect to the percentage of patients that improve 50% any of the 3 signs (Urinary frequency, diurnal / nocturnal frequency, urgency and urinary incontinence). - To determine prognostic factors associated with insufficient improvement (less than 50% in the 3 main signs of hyperactive bladder syndrome (urinary frequency, urgency and urinary incontinence frequency) after treatment with T-PTNS and Solifenacin.

NCT ID: NCT03327948 Active, not recruiting - Clinical trials for Urinary Incontinence, Urge

Axonics SacRal NeuromodulaTIon System for Urinary Urgency Incontinence TreatmeNt

ARTISAN-SNM
Start date: November 21, 2017
Phase: N/A
Study type: Interventional

The ARTISAN-SNM study is designed to evaluate the safety and effectiveness of the Axonics Sacral Neuromodulation System as an aid in the treatment of the symptoms of urinary urgency incontinence (UUI) in patients who have failed or could not tolerate more conservative treatments.

NCT ID: NCT03203798 Active, not recruiting - Clinical trials for Stress Urinary Incontinence

Effects of Training of Pelvic Floor Muscles (MAP) on Stress Urinary Incontinence

Start date: September 1, 2017
Phase: N/A
Study type: Interventional

In the current scientific literature, it is clear that SUI can cause several social, hygienic and personal relationship problems. It has also been proven that this condition affects many more menopausal women than menacme, and this is believed to be due to the hypoestrogenism characteristic of this phase. On the other hand, weakness of the pelvic floor muscles (PFM) is also related to the genesis of SUI. The role of these muscles would be to keep the bladder neck elevated (above the pubic symphysis) during increases in abdominal pressure, and its weakness would lead to excessive lowering of the bladder neck at these times, leading to SUI due to bladder neck hypermobility. The conservative treatment of this condition, therefore, encompasses the strengthening of PFMs, which would avoid excessive descent of the bladder neck during increases in abdominal pressure, thereby reducing urinary loss. In the current literature there are studies proving the effectiveness of pelvic floor muscle training; however, in relation to the literature on abdominal hipopressive gymnastics, it is observed that the scientific evidence is still poor, however, the technique is still Widely spread through extension courses offered throughout Latin America, France and Spain; With regard to the comparison of these methods with respect to their clinical efficacy and the quality of life and patient satisfaction, there are no consistent studies, and this fact motivated us to carry out this study.

NCT ID: NCT03120117 Active, not recruiting - Clinical trials for Stress Urinary Incontinence

Importance of Patient Positioning at Cough Test When Considering Success Following Sling Procedures

DISST
Start date: August 2013
Phase: N/A
Study type: Interventional

This is a prospective study to assess the feasibility and success of performing an intra-operative standing cough test and the correlation with the long term success of the sling surgery.