Enteral Feeding Intolerance Clinical Trial
Official title:
Effect of Blenderized Enteral Tube Feeds on Pediatric Upper Gastrointestinal Tract Physiology
Blenderized diets consist of a wide range of table foods such as fruits, vegetables, meat and legumes, pureed in a blender and administered via gastrostomy tube. In a recent study, the investigators reported that children receiving blenderized feeds via gastrostomy had fewer total admissions and respiratory admissions, total emergency room visits, and improved gastrointestinal symptom scores compared to those fed formula. The goal of this project is to understand how these diets affect gastroesophageal reflux burden.
The investigators hypothesize that rates of gastroesophageal reflux will be lower in blenderized diets compared to formula. The investigators will determine if reflux burden as measured by multichannel intraluminal impedance/esophageal pH monitoring performed for clinical purposes differs between low viscosity conventional formula, medium viscosity commercial blenderized diet, and high viscosity commercial blenderized diet in 45 children receiving conventional formula via gastrostomy. All participants will receive each of the three test diets in random order in a 3-way crossover design. Results of gastric emptying scans will be recorded if done for clinical purposes. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT05473546 -
Diarrhea and Stipsis in Critically Ill Patients (NUTRITI)
|
||
| Active, not recruiting |
NCT05525585 -
Early Human Milk Fortification After Early, Exclusive, Enteral Nutrition in Very Preterm Infants
|
N/A | |
| Completed |
NCT04156529 -
The Effect of Feeding Positions During Tube Feeding on Stress, Pain Level and Feeding Tolerance of Preterm Infants
|
N/A | |
| Completed |
NCT04119089 -
Gastric Ultrasound to Monitor Gastric Residual Volume
|
||
| Active, not recruiting |
NCT04337710 -
Exclusive Enteral Nutrition in Preterm Neonates
|
N/A | |
| Completed |
NCT04804631 -
Tube Feeding in Children Having a Bone Marrow Transplant
|
||
| Recruiting |
NCT06076460 -
Early Total Enteral Feeding Versus Convention Enteral Feeding in Preterm Infants 27-32 Weeks of Gestation
|
N/A | |
| Completed |
NCT03497091 -
Retrospective Review of Amino Acid Formula Use at a Children's Center
|
||
| Recruiting |
NCT04551846 -
The Influence of Polymeric Versus Oligomeric Enteral Feeding on Tolerance and Nutritional Status in Paediatric Intensive Care
|
N/A | |
| Completed |
NCT04946045 -
Feeding Readiness and Oral Feeding Success in Preterm Infants
|
N/A | |
| Recruiting |
NCT04013893 -
Evaluation of Enteral Nutrition in Critically Ill Children
|
||
| Completed |
NCT03643458 -
Splanchnic Oxygenation Response to Feeds in Preterm Neonates: Effect of Red Blood Cell Transfusion
|
||
| Recruiting |
NCT03795870 -
Enteral Nutrition Tolerance and the Gut Microbiome Study
|
N/A | |
| Completed |
NCT03048409 -
Retrospective Tube Feeding Tolerance in Adults With Intolerance After Switch to a Peptide-Based Formula
|
||
| Completed |
NCT03085277 -
Bovine Colostrum for Preterm Newborns
|
N/A | |
| Completed |
NCT04241146 -
Optimal Feeding Tube Placement
|
N/A | |
| Completed |
NCT01953081 -
A Randomized, Double-Blind Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of a Single Dose of Intravenous TD-8954 Compared With Metoclopramide in Critically Ill Patients With Enteral Feeding Intolerance
|
Phase 1/Phase 2 | |
| Completed |
NCT03548324 -
Enteral Nutrition Tolerance And REspiratory Support (ENTARES)
|
N/A | |
| Completed |
NCT04413474 -
Ultrasonographic Assessment of Gastric Residual Volume
|
||
| Recruiting |
NCT05265143 -
Comparision of Two Different Feeding Method in Preterms
|
N/A |