Enteral Feeding Intolerance Clinical Trial
Official title:
Exclusive Enteral Nutrition in Preterm Neonates- A Randomized Controlled Trial
To test the hypothesis that early exclusive enteral nutrition with the minimal use of parenteral nutrition will improve preterm infants' nutritional outcomes when compared to delayed progression of enteral nutrition and prolonged use of parenteral nutrition.
Qualifying participants will be randomly assigned to one of two study groups: 1) Exclusive Enteral Feeds or 2) Progressive Enteral Feeds with supplemental parenteral nutrition. Regardless of study group assignment, donor human milk will be offered if the mother's expressed breast milk is not enough to complete the intervention as assigned. Intervention group: Feeds will be initiated with a target volume of 60-80 ml/kg/day and then advanced by 20-30 ml/kg/day until the total volume of 150ml/kg/day is achieved. Control group: Enteral feeds will be initiated with a target volume of 20-30 ml/kg/day and then advanced by 20-30 ml/kg/day until the total volume of 150 ml/kg/day is achieved. If parent agrees, stool "dirty" diapers will be collected 2 times during this study. One time around the time of birth and one time at 28 days or discharge (whichever occurs first). ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT05473546 -
Diarrhea and Stipsis in Critically Ill Patients (NUTRITI)
|
||
| Active, not recruiting |
NCT05525585 -
Early Human Milk Fortification After Early, Exclusive, Enteral Nutrition in Very Preterm Infants
|
N/A | |
| Completed |
NCT04156529 -
The Effect of Feeding Positions During Tube Feeding on Stress, Pain Level and Feeding Tolerance of Preterm Infants
|
N/A | |
| Completed |
NCT04119089 -
Gastric Ultrasound to Monitor Gastric Residual Volume
|
||
| Completed |
NCT04804631 -
Tube Feeding in Children Having a Bone Marrow Transplant
|
||
| Recruiting |
NCT06076460 -
Early Total Enteral Feeding Versus Convention Enteral Feeding in Preterm Infants 27-32 Weeks of Gestation
|
N/A | |
| Completed |
NCT03497091 -
Retrospective Review of Amino Acid Formula Use at a Children's Center
|
||
| Recruiting |
NCT04551846 -
The Influence of Polymeric Versus Oligomeric Enteral Feeding on Tolerance and Nutritional Status in Paediatric Intensive Care
|
N/A | |
| Completed |
NCT04946045 -
Feeding Readiness and Oral Feeding Success in Preterm Infants
|
N/A | |
| Recruiting |
NCT04013893 -
Evaluation of Enteral Nutrition in Critically Ill Children
|
||
| Completed |
NCT03643458 -
Splanchnic Oxygenation Response to Feeds in Preterm Neonates: Effect of Red Blood Cell Transfusion
|
||
| Recruiting |
NCT03795870 -
Enteral Nutrition Tolerance and the Gut Microbiome Study
|
N/A | |
| Completed |
NCT03048409 -
Retrospective Tube Feeding Tolerance in Adults With Intolerance After Switch to a Peptide-Based Formula
|
||
| Completed |
NCT03085277 -
Bovine Colostrum for Preterm Newborns
|
N/A | |
| Completed |
NCT04241146 -
Optimal Feeding Tube Placement
|
N/A | |
| Completed |
NCT01953081 -
A Randomized, Double-Blind Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of a Single Dose of Intravenous TD-8954 Compared With Metoclopramide in Critically Ill Patients With Enteral Feeding Intolerance
|
Phase 1/Phase 2 | |
| Completed |
NCT03548324 -
Enteral Nutrition Tolerance And REspiratory Support (ENTARES)
|
N/A | |
| Completed |
NCT04413474 -
Ultrasonographic Assessment of Gastric Residual Volume
|
||
| Recruiting |
NCT05265143 -
Comparision of Two Different Feeding Method in Preterms
|
N/A | |
| Not yet recruiting |
NCT05812664 -
The Effects of Bolus, Intermittent and Continuous Enteral Feeding on Blood Glucose and Feeding Intolerance in ICU Patients With Sepsis
|
N/A |