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Enhanced Recovery After Surgery clinical trials

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NCT ID: NCT06273488 Recruiting - Clinical trials for Arthroplasty, Replacement, Knee

The Role of Auricular Point Diagnosis and Treatment in ERAS During TKA

Start date: March 23, 2024
Phase:
Study type: Observational

To further improve the surgical outcomes of patients undergoing total knee arthroplasty (TKA). This study aims to use ear acupoint therapy to address the following clinical issues: 1 The degree of postoperative inflammation and edema in the patient; 2. Patient pain; 3. Patient functional recovery. 4. Surgical scar repair for patients; 5. Patient perioperative anxiety and postoperative satisfaction. Exploring the safety and effectiveness of ear acupoint therapy in the postoperative application of TKA, leveraging the advantages of suitable traditional Chinese medicine techniques in simplicity, convenience, effectiveness, and cost-effectiveness, and further improving the ERAS Chinese and Western medicine collaborative plan for TKA.

NCT ID: NCT06257745 Recruiting - Clinical trials for Cardiac Surgical Procedures

Audit of the Revised PACU Centric ERACS Program

ERACS2
Start date: January 1, 2024
Phase:
Study type: Observational [Patient Registry]

A previous audit (S63843) found an association between improved compliance with these interventions and postoperative outcomes (hospital length of stay (LOS) and presence of ≥1 postoperative complication). The investigators found that every 10% increase in compliance was associated with an increased risk (HR=1.25, p=0.0008) for early discharge. In addition, improved compliance was also associated with a reduction (OR=0.60, p=0.0003) of postoperative complications. Based on these findings, improving compliance with current guidelines remains a hurdle that clinicians should overcome. The investigators previous retrospective study was unable to identify the reason for non-compliance and the relation to postoperative outcomes. Therefore, a prospective audit is warranted to assess reach, fidelity, and dose of the different interventions.

NCT ID: NCT06221020 Recruiting - Clinical trials for Postoperative Complications

To Assess the Impact of theERAS Consensus on Patients With Endoscopic Pituitary Tumor Surgery

Start date: December 12, 2023
Phase:
Study type: Observational [Patient Registry]

The goal of this observational study is to evaluate the effectiveness and impact of Enhanced Recovery After Surgery (ERAS) on patients with pituitary gland tumors.

NCT ID: NCT06137976 Recruiting - Clinical trials for Postoperative Complications

Surgeon Perception of Gastric Decompression at Time of Gynecologic Laparoscopy

Start date: November 20, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to test whether it is necessary to decompress the stomach during gynecologic laparoscopy. The main questions it aims to answer are: - Is there appropriate visualization during surgery without stomach decompression? - Can the surgeon tell the stomach is decompressed? - Is the stomach at risk for injury during surgery? - How is the patient's postoperative experience affected? Participants will undergo their planned surgery as usual and will be asked to complete log about their recovery for the first week after surgery. Researchers will compare patients who have their stomach decompressed during surgery to those who do not undergo stomach decompression to see if it is necessary.

NCT ID: NCT05770739 Recruiting - Clinical trials for Enhanced Recovery After Surgery

A RCT Study of ERAS in Infants With Choledochal Cyst

Start date: January 1, 2022
Phase: N/A
Study type: Interventional

Recently, with reference to the successful experience of accelerated rehabilitation surgery in the field of adult surgery, the investigators have conducted studies on ERAS in pediatric and even infant cholangiectasia surgery to discuss its feasibility and safety. The results showed that some items of ERAS could be safely applied in perioperative management of CBD, and could reduce traumatic stress and promote postoperative recovery. Therefore, the investigators assumed that the ERAS protocols could be safely applied in the treatment of CBD in children and even infants, reducing traumatic stress in children with CBD, promoting postoperative rehabilitation, reducing complications and hospitalization time, reducing hospitalization costs, and saving medical resources.

NCT ID: NCT05613439 Recruiting - Clinical trials for Patient Satisfaction

The Fast-track Centre for Hip and Knee Replacement Database

FCD
Start date: September 1, 2022
Phase:
Study type: Observational

This is a prospective study-registry on preoperative patient characteristics and postoperative complications in patients having fast-track hip and knee replacement surgery in 8 Danish dedicated arthroplasty departments from all five health regions in Denmark. The registry consists of detailed patient and physician reported preoperative characteristics and including prescribed medication and lab results. Follow-up is based on electronical medical records by dedicated nurses with physician backup and includes Clavien-Dindo and Comprehensive Complication Index scoring. All patients having day-surgery also completes a patient reported questionaire on health-care utilization and return to work by day 30. Finally, a machine-learning algorithm for identification of "high-risk" patients based on he preoperative data is included.

NCT ID: NCT05564819 Recruiting - Postoperative Pain Clinical Trials

Efficacy and Safety of Acetaminophen in Postoperative Pain Management of Infants

Start date: September 14, 2022
Phase: Phase 1
Study type: Interventional

Pain will bring early and long-term adverse reactions to infants. The investigators need to pay attention to whether there is pain in infants after surgery. Since infants cannot self-report pain,The investigators need to use appropriate pain assessment scale to evaluate the pain of these infants, so as to understand the status of postoperative pain in children. The result of pain score not only enables investigators to understand the pain status of children, but also helps investigators to give corresponding intervention and treatment according to the pain degree of children. Postoperative pain management is one of the core contents of ERAS. Effective pain management is beneficial to the early postoperative recovery of infants and reduces the adverse reactions caused by pain. Sveral studies have confirmed that the combination of acetaminophen and opioids could reduce the use of opioids after surgery. But even if opioid use is reduced, it still causes many side effects for children. This study evaluated the safety and efficacy of acetaminophen alone for postoperative analgesia in infants.

NCT ID: NCT05541640 Recruiting - Clinical trials for Enhanced Recovery After Surgery

Intraoperative Lidocaine Infusion and Surgery-induced Release of Pro-inflammatory Cytokines After Abdominal Surgery

Start date: October 1, 2022
Phase: N/A
Study type: Interventional

Lidocaine is an amide local anaesthetic and an antiarrhythmic agent, first synthesized in 1942, and after approval for human use was launched in 1948 in Sweden The first observations of post operative analgesic effects of perioperative intravenous lidocaine (IVL) were initially proposed in 1951 subsequently many more enthusiastic reports followed. Postoperative formal clinical evaluations in the perioperative setting were conducted in the late 1950s where IV Lidocaine was demonstrated to have a postoperative analgesic effect without posing the risk of respiratory depression, reducing the occurrence of postoperative nausea and vomiting (PONV), and enhance post-surgical recovery. IV Lidocaine also potentiated the depth of anesthesia and led to a better tolerance of endotracheal intubation.Around 40% of patients experience a delay in resumption of normal bowel function after colorectal surgery. This delay leads to symptoms of nausea, vomiting, constipation, and abdominal distension, which then require unpleasant supportive interventions such as intravenous fluids and nasogastric tube insertion. There is no remedy to address this delay. ALLEGRO, "A placebo-controlled randomized trial of intravenous Lidocainein accelerating Gastrointestinal Recovery surgery," is the latest ongoing multicenter research study across the United Kingdom, investigating the use of intravenous lidocaine to improve recovery after colorectal surgery

NCT ID: NCT05528484 Recruiting - Clinical trials for Enhanced Recovery After Surgery

Self-reported Outcomes of Patients in ERAS Nursing

Start date: October 1, 2019
Phase: N/A
Study type: Interventional

We aimed to evaluate the effect of ERAS nursing program on self-reported outcomes of patients undergoing minimally invasive lung cancer surgery, and compared the differences in length of hospital stay, complications, and readmission rate between ERAS and non-ERAS nursing programs

NCT ID: NCT05412355 Recruiting - Clinical trials for Colorectal Neoplasms

Effects of Incomplete ERAS on Clinical Outcomes in Patients With Colorectal Cancer

Start date: June 1, 2022
Phase:
Study type: Observational

Enhanced recovery after surgery (ERAS) has been reported to be associated with improved outcomes in many studies, most of which involve short-term effects. Only a few studies have reported the long-term effects of highly compliant ERAS. However, to the best of our knowledge, there are no large-scale comparisons between incomplete ERAS (compliance < 70%) and non-ERAS. The aim of this comparative study is to analyze and evaluate the long-term outcomes of incomplete ERAS in laparoscopic colorectal cancer surgery.