A RCT Study of ERAS in Infants With Choledochal Cyst

Status Recruiting

Clinical Trial Summary

Recently, with reference to the successful experience of accelerated rehabilitation surgery in the field of adult surgery, the investigators have conducted studies on ERAS in pediatric and even infant cholangiectasia surgery to discuss its feasibility and safety. The results showed that some items of ERAS could be safely applied in perioperative management of CBD, and could reduce traumatic stress and promote postoperative recovery. Therefore, the investigators assumed that the ERAS protocols could be safely applied in the treatment of CBD in children and even infants, reducing traumatic stress in children with CBD, promoting postoperative rehabilitation, reducing complications and hospitalization time, reducing hospitalization costs, and saving medical resources.

Clinical Trial Description

1. Optimize preoperative, intraoperative and postoperative perioperative management by learning from the successful experience of accelerated rehabilitation surgery model in other fields. For example: necessary and sufficient preoperative education of children and guardians; short fasting before surgery; oral carbohydrate at 2h before surgery; breast feeding at 4h before surgery (formula feeding at 6h before surgery); improved intestinal preparation; irregular placement of nasogastric tube; the use of general anesthesia plus epidural or sacral block anesthesia during surgery; attention to the whole process of heat preservation; strict control of infusion volume; and selection of minimally invasive hands Methods of operation; early postoperative activity, multi-mode analgesia, etc. 2. According to the pathophysiological characteristics of infants with cholangiectasia, several aspects were studied: minimally invasive surgery；promote gastrointestinal motor function recovery；develop principles and plans for early postoperative feeding；Rational placement of abdominal drainage tube; precise choice of anesthesia method, etc. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05770739
Study type	Interventional
Source	Nanjing Children's Hospital
Contact	Xiaofeng Lv
Phone	+86 13770848430
Email	xflv1981@163.com
Status	Recruiting
Phase	N/A
Start date	January 1, 2022
Completion date	December 31, 2024

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT04963751` - ERAS in Pediatric & Adolescent Gynecology Preoperative Counseling	N/A
Recruiting	`NCT04072419` - Application of Enhanced Recovery After Surgery for Congenital Esophageal Atresia During Perioperative Period
Recruiting	`NCT05564819` - Efficacy and Safety of Acetaminophen in Postoperative Pain Management of Infants	Phase 1
Recruiting	`NCT05613439` - The Fast-track Centre for Hip and Knee Replacement Database
Completed	`NCT04543214` - Outcome of Enhanced Recovery After Surgery (ERAS) Protocols in Patients Undergoing Small Bowel Surgery
Not yet recruiting	`NCT05576766` - Enhanced Recovery After Surgery (ERAS) Pathway in Patients Undergoing Robot-Assisted Laparoscopic Radical Prostatectomy	N/A
Recruiting	`NCT05081804` - The Effect of Enhanced Recovery After Surgery (ERAS) for Cesarean Section on Neonatal Blood Glucose	N/A
Completed	`NCT04538235` - Analgesic Non Inferiority of the Thoracic Bi-block in Comparison With Thoracic Epidural for VATS.
Not yet recruiting	`NCT05914090` - The Application of Enhanced Recovery After Surgery (ERAS) for Cardiovascular Surgery in Adult	N/A
Recruiting	`NCT05541640` - Intraoperative Lidocaine Infusion and Surgery-induced Release of Pro-inflammatory Cytokines After Abdominal Surgery	N/A
Not yet recruiting	`NCT05511194` - Safety and Efficacy of ERAS Therapeutic Protocol for Complicated Appendicitis in Children	N/A
Recruiting	`NCT05528484` - Self-reported Outcomes of Patients in ERAS Nursing	N/A
Recruiting	`NCT04596800` - Prehabilitation Plus ERAS Versus ERAS in Gynecologic Oncology: a Randomized Clinical Trial	Phase 3
Completed	`NCT04648644` - Application of ERAS Protocol in Emergency Surgery
Completed	`NCT02949518` - Enhanced Recovery After Spine Surgery	N/A
Recruiting	`NCT06137976` - Surgeon Perception of Gastric Decompression at Time of Gynecologic Laparoscopy	N/A
Completed	`NCT06118593` - Why in Hospital After Wedge Resection
Active, not recruiting	`NCT06369194` - POWER AUDIT, Postoperative Outcomes Within an Enhanced Recovery After Surgery Protocol
Recruiting	`NCT04576533` - Patients Undergoing Laparoscopic Colorectal Surgery Walk Out From Operating Room After Surgery ( WOFOR-C1 )	N/A
Not yet recruiting	`NCT04397627` - ERAS Program Items Adherence, PROMs and RIOT After Colorectal Surgery

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.