Clinical Trials Logo
  1. Home
  2. Endotracheal Intubation
  3. NCT04008420

The Association of Intraoperative Oxygen Reserve Index and Postoperative Pulmonary Complications in Robot-assisted Esophagectomy

Endotracheal Intubation Clinical Trial

Official title:
The Association of Intraoperative Oxygen Reserve Index and Postoperative Pulmonary Complications in Robot-assisted Esophagectomy

Clinical Trial Summary

The World Health Organization (WHO) has proposed the use of 80% high-dose inhalation oxygen (FiO2) during surgery to reduce postoperative infection in adult patients undergoing general anesthesia. However, high-dose inhaled oxygen increases the risk of oxygen toxicity by increasing reactive oxygen species, and according to a recent research, hyperoxia in the ICU is one of the causes of mortality. In patients with general anesthesia requiring intubation, high-dose inhaled oxygen was associated with postoperative pulmonary complications in a dose-proportional manner and was significantly associated with mortality within 30 days after surgery. Therefore, it is necessary to study the optimum oxygen concentration during surgery to reduce postoperative pulmonary complications in general anesthesia patients who require intubation. Esophagectomy for esophageal cancer still has higher morbidity and mortality rates than other common procedures. There are several factors such as aneurysmal leakage, esophageal substitute necrosis, cardiac complications, and pulmonary complications. Pulmonary complications have been reported to be a very important factor. Therefore, various methods have been proposed to reduce pulmonary complications after esophageal cancer surgery. One of them is minimally invasive surgery. However, even in the case of a thoracoscopic operation using a robot, one lung ventilation is inevitable for securing the visual field during surgery, and hypoxia and hyperoxia are known to be associated with postoperative acute lung injury. Therefore, in order to reduce postoperative pulmonary complications in the esophagectomy using robots, it is necessary to study the optimum oxygen concentration during surgery. The recently developed oxygen reserve index (ORI) uses a non-invasive sensor attached to the finger, similar to pulse oximetry, to detect persistent hyperoxia of more than 100 mmHg and less than 200 mmHg. Therefore, if the oxygen reserve index is used for robotic esophagectomy, which requires one lung ventilation, the degree of oxygenation of the patient can be monitored continuously and accurately. The authors will measure the oxygen reserve index in robotic esophagectomy, and analyze the correlation between oxygen reserve index and postoperative pulmonary complications. Furthermore, the cut-off value of the oxygen reserve index, which can reduce pulmonary complications, will be calculated.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04008420
Study type Observational
Source Yonsei University
Contact So Yeon Kim, MD
Phone 82-2-2228-2429
Email KIMSY326@yuhs.ac
Status Recruiting
Phase
Start date July 31, 2020
Completion date June 2024
View Details
See also
  Status Clinical Trial Phase
Completed NCT06089187 - Comparing Endotracheal Tube Cuff Pressure in Laparoscopic Abdominal Surgery: Saline vs. Air Inflation N/A
Completed NCT02395445 - A Comparison of Tracheal Intubation Using the Totaltrack vs the Macintosh Laryngoscope in Routine Airway Management N/A
Completed NCT02395432 - A Comparison of Tracheal Intubation Using the Totaltrack vs the Macintosh Laryngoscope in Difficult Airway N/A
Unknown status NCT01041066 - Nicardipine Versus Labetalol During Intubation N/A
Completed NCT03284892 - Screening and Intervention of Postextubation Dysphagia N/A
Recruiting NCT02395419 - A Comparison of Tracheal Intubation Using the Totaltrack vs the Airtraq Laryngoscope in Routine Airway Management N/A
Recruiting NCT02395406 - A Comparison of Tracheal Intubation Using the Totaltrack vs the Airtraq Laryngoscope in Difficult Airway Management N/A
Enrolling by invitation NCT02277015 - Intubation During Pediatric Resuscitation N/A
Completed NCT01169467 - Cerebral Perfusion Pressure Using Precedex and Other Sedatives Phase 3
Completed NCT00620386 - Endotracheal Intubation Using Bonfils Fibrescope Without Neuromuscular Blockade Phase 2/Phase 3
Completed NCT05069844 - Preoperative Gum Chewing for Different Durations to Prevent Sore Throat After Endotracheal Intubation N/A
Enrolling by invitation NCT05620108 - Intubating Conditions of Neuromuscular Blockade N/A
Completed NCT02741921 - Conventional Double-lumen Tube vs VivaSight DL N/A
Recruiting NCT02295657 - Double Lumen Tube Intubation N/A
Completed NCT01488370 - Comparison of 2 Laryngoscopes for Endotracheal Intubation in Children Younger Than 2 Years Old N/A
Recruiting NCT01006668 - Sevoflurane Versus Propofol for Intubation in Neonatal Intensive Care Phase 3
Recruiting NCT04483895 - Comparison Between the Oro-Helical Length Technique and the 7-8-9 Rule in Determination of the Ideal Endotracheal Tube Insertion Depth in Neonates N/A
Completed NCT04141267 - Inhaled Sedation Using the Anesthetic-conserving Device ( ANACONDA) in Prehospital Emergency Medecine.
Completed NCT01490580 - Premedication Trial for Tracheal Intubation of the NEOnate Phase 2/Phase 3
Completed NCT03878797 - The Depth of Endotracheal Tube Insertion