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Endometriosis clinical trials

View clinical trials related to Endometriosis.

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NCT ID: NCT03586804 Not yet recruiting - Clinical trials for Women's Health: Endometriosis

Postural Sway at Menstrual Cyclus

Start date: July 30, 2018
Phase:
Study type: Observational

The study was planned with the aim of comparison of postural sway responses at menstrual cycles in women with and without the dysmenorrheal syndrome. Women will stand on a postural sway evaluation system on the first day of the menstrual cycles and a well-being day which they will select. Every participant will be evaluated same tool. They will be assessed for three times at every session: 1st evaluation will be performed at the normal standing position. 2nd evaluation will be performed at the normal standing position while individuals saying the numbers from 200 to 1. 3rd evaluation will be performed at the normal standing position while individuals holding the mini blocks on their hands.

NCT ID: NCT03585309 Not yet recruiting - Clinical trials for Ovarian Endometrioma

The Impact of Electrocoagulation on Ovarian Reserve After Laparoscopic Excision of Ovarian Cysts.

Start date: July 15, 2018
Phase: N/A
Study type: Interventional

The aim of the study is to evaluate the effect of bipolar electrocoagulation on ovarian reserve.

NCT ID: NCT03565848 Not yet recruiting - Endometriosis Clinical Trials

Mesenteric Sparing Surgery in Laparoscopic Colorectal Resection for Endometriosis

IRE-1
Start date: May 1, 2022
Phase:
Study type: Observational

Colorectal resection is a standard surgical treatment of bowel deep infiltrating endometriosis (DIE). Nevertheless, concerns about different bowel functional outcomes related to radical surgery versus conservative surgery as shaving technique is a topic leading to much debate. Different surgical approach are used to perform colorectal resection and there is not a standardized technique. For the same concerns, studies have addressed the mesenteric vascular and nerve preservation both in oncological and benign intestinal disease with improved functional outcome. Therefore, the aim of this prospective study is to analyze feasibility and safety of mesenteric vascular and nerve Sparing Surgery in laparoscopic segmental colorectal resection for DIE with short and long term follow up. Women with DIE ,that underwent laparoscopic segmental colorectal resection, will undergo resection performed with inferior mesenteric artery and branching arteries preservation by dissecting adherent to the intestinal wall with mesenteric vascularization and innervation entirely preserved. Personal history, clinical data, surgical data, short and long term surgical complications and long term outcomes will be recorded. Symptoms and bowel function will be evaluated before and after surgery.

NCT ID: NCT03549728 Not yet recruiting - Endometriosis Clinical Trials

Effect of Granulocyte Colony-stimulating Factor on Clinical Pregnancy Rate in Patients With Endometriosis

Start date: June 2018
Phase: Phase 2
Study type: Interventional

The aim of this study is to evaluate the effect of granulocyte colony-stimulating factor on clinical pregnancy rate in patients with endometriosis undergoing in-vitro fertilization after recurrent implantation failure.

NCT ID: NCT03464799 Not yet recruiting - Endometriosis Clinical Trials

Does Immunotherapy Have a Role in the Management of Endometriosis?

Start date: September 2018
Phase:
Study type: Observational

Pathological specimens of 40 women that had been operated for endometriosis will be included in this study. These tissues will be stained with a marker named as PDL-1 in pathological examination. "programmed cell death (PD-1)" is expressed on T cells. The immunotherapies in which antibodies against these PD-1 and its ligands (PDL-1) have been used are accepted as very effective in the treatment of many cancers. If these ligands can be shown in the endometriosis, it will be an important step for the treatment of endometriosis.

NCT ID: NCT03212612 Not yet recruiting - Endometriosis Clinical Trials

Galectin-3 in Patients With Endometriosis

Start date: August 2017
Phase: N/A
Study type: Observational

The exact cause of endometriosis is unknown ,so our study is to investigate the relationship between Galectin-3 and endometriosis by comparing between its level in healthy and endometriosis women. Also, we will measure the level of oxidative stress markers in endometrium of both healthy and endometriosis women and investigate the correlaton between them and galectin-in endometriosis women.

NCT ID: NCT02779387 Not yet recruiting - Clinical trials for Infertility Associated With Endometriosis

Reproductive Outcome of EM Treated by GnRH-a Associated With Laparoscopy

Start date: May 2016
Phase: N/A
Study type: Interventional

This study is a multicenter, randomized-control-trial. This study select 1184 Infertile patients associated with endometriosis diagnosed by laparoscopy surgery. Patients are going to be divided into two groups according to 1:1 ratio randomly assigned to receive GnRH-a. Cumulative pregnancy rate, end of treatment to natural pregnancy time, accept the assisted reproductive treatment rate, miscarriage rate, live birth rate will be recorded.

NCT ID: NCT02685644 Not yet recruiting - Endometriosis Clinical Trials

Association Between Laparoscopic Removal of Endometriomas and Anti-mullerian Hormone Levels

Start date: April 2016
Phase: N/A
Study type: Observational

Laparoscopic excision of endometriotic cysts is the main stream surgical intervention for treatment of endometriosis. However there is evidence that intervention may effect ovarian reserve by destruction of healthy ovarian tissue during surgery. Available evidence on the topic are contradictory and employed research methodology are diverse. There is need for an adequately powered research with proper methodology to assess actual effects of surgery.

NCT ID: NCT02484196 Not yet recruiting - Endometriosis Clinical Trials

Dyspareunia in Women With Endometriosis: Impact of Surgery on Sexual Health

Start date: June 1, 2021
Phase:
Study type: Observational

Endometriosis is a disease that affects different areas of individual functioning, including the area of sexual life. Women with endometriosis have an impairment of desire and sexual arousal, orgasmic capacity reducted because of the pain and deep dyspareunia. The aim of the study is to evaluate the effectiveness of surgery on dyspareunia in women with endometriosis, taking into account other variables involved in determining dyspareunia: the quality of the couple relationship, anxiety and depression, body image, coping strategies and resilience.

NCT ID: NCT02393482 Not yet recruiting - Quality of Life Clinical Trials

Psychological Impact of Amenorrhea in Women With Endometriosis

Start date: June 2021
Phase: Phase 4
Study type: Interventional

The purpose of the study is to evaluate the impact on quality of life, psychological health, sexuality and chronic pain of therapies which determine amenorrhea in symptomatic women with endometriosis, through the administration of self reported questionnaires. Amenorrhea in the first group is caused by balanced assumption of estroprogestins, in the second group is caused by GnRHa-induced hypoestrogenism.