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Endometriosis clinical trials

View clinical trials related to Endometriosis.

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NCT ID: NCT00800618 Completed - Endometriosis Clinical Trials

A Study To Investigate How The Body Handles Multiple Doses Of PF-0243873 And To Investigate The Effect Of PF-02413873 On Sex Hormone Levels In Healthy Young Women

Start date: November 2008
Phase: Phase 1
Study type: Interventional

The study will investigate how well multiple doses of PF-02413873 are tolerated by healthy young women, how the body handles multiple doses of PF-02413873 and which effect PF-02413873 has on sex hormones in healthy young women

NCT ID: NCT00797225 Completed - Endometriosis Clinical Trials

Efficacy and Safety Study of Elagolix Versus Placebo or Leuprorelin Acetate in Endometriosis

Start date: November 26, 2008
Phase: Phase 2
Study type: Interventional

This study is designed to evaluate the safety and beneficial effects of elagolix (NBI-56418) compared to placebo and leuprorelin (an approved endometriosis therapy) over a three month period followed by an additional three months of treatment on elagolix.

NCT ID: NCT00758953 Completed - Endometriosis Clinical Trials

Pain Associated With Endometriosis

Start date: February 2007
Phase: Phase 2
Study type: Interventional

This study will evaluate the efficacy and safety of an investigational medication compared with placebo in the treatment of pain associated with endometriosis.

NCT ID: NCT00735852 Completed - Endometriosis Clinical Trials

Decapeptyl SR With Livial Add Back Therapy in the Management of Chronic Cyclical Pelvic Pain in Pre Menopausal Women

Start date: December 2008
Phase: Phase 4
Study type: Interventional

This is a single-centre, open-label, within patient comparison study to assess the efficacy and safety of Decapeptyl SR when administered in combination with Livial for the treatment of women with chronic cyclical pelvic pain. This will be for a 2 year period with a 6 month post treatment follow up. The study aims to recruit 40 patients.

NCT ID: NCT00632697 Completed - Clinical trials for Endometriosis-Associated Infertility

Pentoxifylline and Endometriosis

LETS1
Start date: October 2001
Phase: Phase 3
Study type: Interventional

To prove efficacy of an immunomodulator called pentoxifylline in the treatment of endometriosis in infertile patients undergoing laparoscopy surgery

NCT ID: NCT00625950 Completed - Endometriosis Clinical Trials

Endometriosis Patients Undergoing Quinagolide Treatment

Start date: February 2008
Phase: Phase 4
Study type: Interventional

Dopamine agonists, such as quinagolide, are able to act on the VEGFR-2 blocking antibodies, diminishing Vascular Endothelial Growth Factor effect on angiogenesis in human endometriotic lesions.

NCT ID: NCT00621179 Completed - Infertility Clinical Trials

Endometrial Markers and Response of Endometriosis Patients to Prolonged GnRH Agonist Prior to IVF

IntegrinIVF
Start date: March 2003
Phase: Phase 4
Study type: Interventional

This prospective randomized trial evaluates whether one can predict which infertile women with endometriosis who are candidates for in vitro fertilization will benefit from prolonged therapy with a GnRH agonist by the determination of the absence of endometrial expression of the integrin, alpha v, beta 3 vitronectin. This is a prospective randomized trial in which all patients will undergo endometrial biopsy prior to initiation of ovarian stimulation for in vitro fertilization and then undergo randomization to a three month course of a depot preparation of the GnRH agonist leuprolide acetate in depot suspension prior to ovarian stimulation or standard therapy. prio

NCT ID: NCT00619866 Completed - Endometriosis, Pain Clinical Trials

An Efficacy and Safety Study of Elagolix (NBI-56418) in Women With Endometriosis

Start date: February 19, 2008
Phase: Phase 2
Study type: Interventional

This study is designed to see how elagolix works compared to placebo in women with endometriosis and to see the effect, if any, on bone mineral density.

NCT ID: NCT00604864 Completed - Endometriosis Clinical Trials

Effect of Anti TNFa Upon Deep Endometriosis Associated Pain

Infliximab
Start date: February 2004
Phase: Phase 2
Study type: Interventional

Deep endometriosis associated pain is believed to be caused by inflammation. Anti TNFa has been proved to be an effective treatment for other inflammation related conditions as Crohn's disease Endometriosis is associated with an inflammatory response in the pelvis, which is mediated by a number of cytokines including TNF-α. It has therefore been suggested that infliximab, an anti-TNF-α monoclonal antibody, might relieve pain in affected women.

NCT ID: NCT00485355 Completed - Clinical trials for Uterine Fibroids, Menorrhagia, Endometriosis

Study Comparing Conventional vs. Robotic-assisted Laparoscopic Hysterectomy

Start date: June 2007
Phase: N/A
Study type: Interventional

The purpose of this study is to compare two ways of performing laparoscopic hysterectomy - robotic-assisted vs. conventional laparoscopy.