Endodontic Inflammation Clinical Trial
Official title:
Comparative Evaluation Of Postoperative Pain After Using Sonic Vibringe Irrigation System Versus Conventional Irrigation In Single Rooted Teeth With Symptomatic Irreversible Pulpitis : A Randomized Clinical Controlled Trial
The Vibringe is the first endodontic sonic irrigation system that enables delivery and
activation of the irrigation solution in the root canal, in only one step. The activation of
the disinfectant by acoustic streaming, enriches and completes the irrigation procedure and
improves the success rate of endodontic treatments. It has been shown that this system
significantly improves debridement. It also improves the disruption of the smear layer and
biofilm by activating irrigation solutions.
As there are no previous studies comparing the Vibringe system with other irrigation
techniques under clinical settings, in this regard, the aim of this study is to evaluate
whether irrigation with Vibringe provides more or less benefit in terms of postoperative pain
when compared with the conventional needle technique.
Postoperative pain is defined as the sensation of discomfort after endodontic intervention
and is reported by 25%-40% of patients irrespective of pulp and peri-radicular status.
According to the 2011 systematic review of Pak and White , the prevalence of pain in the
first 24 hours is 40%, falling to 11% after 7 days. Dentinal debris, pulp tissue,
microorganisms and irrigants can be conveyed to the peri-radicular tissues during root canal
preparation and such extrusion of debris can lead to postoperative complications, such as
flare-ups.
Mechanical instrumentation and irrigation are used to remove vital and necrotic remnants of
pulp tissue, debris, microbiota and their by-products from a root canal system. However,
several studies using microcomputed tomography scanning imagery have shown that most of the
areas of the main root canal wall remain untouched by the instruments. This emphasizes the
importance of other means of cleaning and disinfecting all areas of the root canal.
To enhance the effectiveness of cleaning and disinfecting all areas of the root canal,
several irrigants are commonly used as initial and final rinses to overcome the shortcomings
of using a single irrigant, such as sodium hypochlorite (NaOCl), ethylene-diaminetetraacetic
acid or chlorhexidine. In addition to these various irrigants, numerous irrigation devices
and needle tips have been developed with the aim of improving the delivery of irrigant
throughout the root canal using sonic or ultrasonic energy and negative apical pressure.
However, as well as the success of the irrigation devices in removing debris from the root
canal, a safe irrigation delivery system is desirable to prevent periapical tissue damage and
decrease post-endodontic pain. The available data on extrusion of irrigant when using these
devices appears to be limited to laboratory studies.
Rationale :
The Vibringe is the first endodontic sonic irrigation system that enables delivery and
activation of the irrigation solution in the root canal, in only one step. The activation of
the disinfectant by acoustic streaming, enriches and completes the irrigation procedure and
improves the success rate of endodontic treatments. It has been shown that this system
significantly improves debridement. It also improves the disruption of the smear layer and
biofilm by activating irrigation solutions.
Vasconcelos et al at in vitro study at 2017 proved that groups using ultrasonic agitation
presented a greater antibacterial effect than the other ones, even using saline solution as
irrigant. Middha et al studied the effect of continuous ultrasonic irrigation on
postoperative pain in mandibular molars with nonvital pulps concluded that a significant
difference was observed between CUI and syringe irrigation on the first postoperative day
following chemo-mechanical preparation. However, the benefit observed was not clinically
relevant.
It has been shown that the Vibringe results in an equal performance in canal and isthmus
debridement efficacy when compared with needle irrigation in the apical region (9). In
addition, it did not significantly alter sealer penetration compared with conventional
needles. Furthermore, another recent study concluded that the Vibringe extruded more debris
than conventional needle irrigation .
Postoperative pain associated with root canal treatment is a poor indicator of long-term
success; however, the occurrence and the control of pain are of clinical interest. So , this
study will focus on evaluating postoperative discomfort due to the fact that Vibringe is an
actively vibrating system, which may lead to postoperative discomfort.
Objective of the study :
As there are no previous studies comparing the Vibringe system with other irrigation
techniques under clinical settings, in this regard, the aim of this study is to evaluate
whether irrigation with Vibringe provides more or less benefit in terms of postoperative pain
when compared with the conventional needle technique.
;
Status | Clinical Trial | Phase | |
---|---|---|---|
Withdrawn |
NCT03502135 -
Efficacy of Tetracaine/Oxymetazoline Nasal Spray for Endodontic Treatment
|
Phase 4 | |
Completed |
NCT02437708 -
Regenerative Endodontic Procedure of Immature Permanent Teeth With L-PRF: a Pilot Controlled, Clinical Trial
|
Phase 3 | |
Completed |
NCT03635515 -
Occurrence of Post-op Pain Following Gentlewave
|
N/A | |
Completed |
NCT04211519 -
Analysis of Bacterial Microbiome of Endodontically Infected Primary and Permanent Teeth
|
N/A | |
Completed |
NCT06176378 -
A Clinical and Radiographic Evaluation of Low-Level Diode Laser Full Pulpotomy in Vital Permanent Teeth
|
N/A | |
Recruiting |
NCT03883295 -
Evaluation of Clinical and Radiological Success of Vital Amputation Treatment
|
N/A | |
Completed |
NCT04700995 -
Postoperative Pain After Using NiTi Instruments
|
N/A | |
Completed |
NCT03472456 -
Endodontic Medications for Irreversible Pulpitis: Articaine or Eugenol?
|
||
Completed |
NCT03802305 -
Comparison of Osteocentral Versus Locoregional Anesthesia in Case of Mandibular Molar Pulpitis
|
N/A | |
Active, not recruiting |
NCT04399135 -
Accuracy of Pulp Sensibility Test on Teeth With Deep Periodontal Pocket
|
N/A | |
Recruiting |
NCT04628845 -
Endo-perio Lesion's Treatment With Using Diode Laser 940nm
|
N/A | |
Completed |
NCT04228913 -
Effect of Different Obturation Techniques on Postoperative Pain
|
Phase 4 |