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Clinical Trial Summary

The purpose of this study is to develop a protocol for biofilms disinfection with a FDA cleared, clinically approved and commercially available Er,Cr:YSGG laser treatments. This protocol will be testing local single topical application of Lasers within the canal system in patients going through routine endodontic treatment, evaluate its potential as anti-biofilm treatment and compare it to other currently used antibacterial protocols.


Clinical Trial Description

After being informed about the study and its potential risk, for all patients giving written informed consent we will screen potential participants by inclusion and exclusion criteria; clinical assessment, obtain radiographs, medical history/medications and documents to determine eligibility for study entry. Participants who meet the eligibility requirements will be randomized in a 1:1 ratio to Group 1: Standard of care irrigation protocol "Sodium Hypochlorite (NaOCl)", Group 2: Er,Cr:YSGG laser + standard of care irrigation protocol (NaOCl). ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05959629
Study type Interventional
Source University of Pennsylvania
Contact Dana Mominkhan, B.D.S
Phone 773-610-2393
Email danakhan@upenn.edu
Status Recruiting
Phase N/A
Start date October 11, 2023
Completion date July 2027

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