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Endocrine System Diseases clinical trials

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NCT ID: NCT06113952 Withdrawn - Clinical trials for Pediatric Growth Hormone Deficiency

A Study to Compare the Experiences of Taking Daily Growth Hormone Injections to Weekly Ngenla in Children With Low Levels of Growth Hormone

Start date: January 2024
Phase:
Study type: Observational

The purpose of this study is to learn about: - how children stick to taking their injections - their experience with the study medicines (Ngenla and daily growth hormone) prescribed to children with low levels of growth hormone. This study is seeking participants who: - are being treated or are ready to start treatment with daily growth hormone or Ngenla. - use a sharps bin to collect used needles. The study medicines will be given as per regular care agreed with the doctor. The study will compare participant experiences to help us see: - the difference in how the participants stick to taking their daily growth hormone injections compared to participants using once weekly Ngenla. Participants will take part in this study for up to 14 months. During this time, they will have 3 study visits at the study clinic. The participants will use the HealthBeacon™ smart sharps bin for collecting the used needles or injections.

NCT ID: NCT05518006 Withdrawn - Hormone Disturbance Clinical Trials

An Investigation of Premama Balance and Its Effects on Hormonal Imbalances

Start date: December 30, 2022
Phase: N/A
Study type: Interventional

An investigation of the dietary supplement marketed as "Premama Balance" on markers of subjective wellbeing in trial participants such as common symptoms of PMS and menstrual symptoms, as well as its effects on aiding in returning to their perceived regular/normal menstrual cycle.

NCT ID: NCT03856268 Withdrawn - Adiposity Clinical Trials

Understanding the Roles of Hormones in Adipocyte Remodeling Following Menopause

RESUME-2
Start date: April 1, 2019
Phase:
Study type: Observational

The overarching aims of this study are to: 1. Characterize the rate of in vivo adipogenesis, and changes in adipose tissue gene and protein expression, in the scABD and scFEM depots of women undergoing surgical menopause (↓E2, ↑FSH). 2. Characterize the rate of in vivo adipogenesis, and changes in adipose tissue gene and protein expression, in the scABD and scFEM depots of women undergoing gonadal suppression (↓E2, ↓FSH).

NCT ID: NCT01731028 Withdrawn - Clinical trials for Growth Hormone Deficiency

Surveillance of Treatment of Children With Growth Hormone Deficiency With Zomacton®

Start date: January 2013
Phase: N/A
Study type: Observational

The purpose of this study is to investigate the long-term treatment with Zomacton® for pituitary short stature in children with insufficient growth hormone production and/or short stature caused by Turner's syndrome.

NCT ID: NCT01333267 Withdrawn - Osteoporosis Clinical Trials

One Week Comparison Study of PTH and PTHrP Infusions

Start date: January 2015
Phase: Phase 1
Study type: Interventional

This is a dose escalation study to determine the maximum tolerable dose of Parathyroid Hormone-related Protein, PTHrP, or Parathyroid Hormone, PTH, that can be given safely over one week in healthy African-American volunteers. The investigators plan to infuse low doses of intravenous PTHrP or PTH to determine if it leads to a sustained and progressive suppression of bone formation as occurs in humoral hypercalcemia of malignancy (HHM) or an increase in bone formation as occurs in hyperparathyroidism (HPT). Additionally, the investigators will assess the direct influence of PTHrP and PTH on vitamin D metabolism, markers of bone turnover, and fractional excretion of calcium. These results will be compared to previous studies of Caucasian volunteers.