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The Effect of an Antibiotic on the Production of Uremic Toxins by the Gut Microbiome

End Stage Renal Disease Clinical Trial

Official title:
The Effect of an Antibiotic on the Production of Uremic Toxins by the Gut Microbiome

Clinical Trial Summary

The purpose of this study is to determine if multiple doses of vancomycin over the course of 3 months will perturb the intestinal flora (microbiome) and result in reduced serum concentration of the uremic toxin indoxyl sulfate and p-cresyl sulfate. The design of the study will permit investigators to assess the variability of serum uremic retention solute concentrations with and without antibiotic over a three-month period.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03452189
Study type Interventional
Source NYU Langone Health
Contact
Status Completed
Phase Phase 2
Start date November 27, 2017
Completion date August 18, 2018
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