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Cognitive Impairment and Imaging Correlates in End Stage Renal Disease

End Stage Renal Disease Clinical Trial

Official title:
Cognitive Impairment and Imaging Correlates in End Stage Renal Disease

Clinical Trial Summary

The purpose of this study is to understand cognitive impairment in end stage renal disease before and after a kidney transplant.

Clinical Trial Description

Cognitive impairment is very common in patients with End Stage Renal Disease (ESRD). It exact mechanisms are not clear, but patients with ESRD have more cerebral white matter changes. Several studies have shown that cognitive function improves post-transplant, indicating that there may be some reversibility in the process. This study will examine the correlation between cognitive impairment and structural brain changes before and after renal transplantation. We will also study the correlation of cognitive function with serum inflammatory markers before and after transplant. These results will be compared to aged matched healthy controls without kidney disease. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01883349
Study type Observational
Source University of Kansas Medical Center
Contact Andrew Jurgensen, BS
Phone 913-574-0895
Email ajurgensen@kumc.edu
Status Recruiting
Phase
Start date March 2013
Completion date December 2023
View Details
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