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The Effect of Nocturnal Haemodialysis on Arterial Stiffness

End Stage Renal Disease Clinical Trial

Official title:
The Effect of Nocturnal Haemodialysis on Arterial Stiffness

Clinical Trial Summary

Arterial stiffness refers to the accumulation of extracellular deposits of matrix and calcium which reduce blood vessel compliance. Although there is growing evidence that increased arterial stiffness is associated with chronic kidney disease (CKD), its pathogenesis is unclear. Pulse wave velocity (PWV) and augmentation index (AIx) provide tools for estimating arterial stiffness, and therefore predicting cardiovascular morbidity and mortality. The aims of the study are: (1) compare the effects of nocturnal and conventional haemodialysis on arterial stiffness, and (2) examine the relationship between arterial stiffness and clinical and biochemical parameters.

Clinical Trial Description

n/a

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00641875
Study type Observational
Source Melbourne Health
Contact
Status Completed
Phase N/A
Start date December 2005
Completion date February 2008
View Details
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