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Enamel Caries clinical trials

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NCT ID: NCT06425536 Not yet recruiting - Enamel Caries Clinical Trials

Efficacy of Remineralizing Products Used in Molar Grooves: Evaluation With Diagnodent Pen and Diagnocam

Start date: June 1, 2024
Phase: N/A
Study type: Interventional

To evaluate the efficacy of enamel remineralization by biomimetic hydroxyapatite contained in microRepair-based Biorepair Total Protection toothpaste compared to the use of Bio Enamel Caries and Erosion toothpaste based on Fluoro-Hydroxyapatite and BioActive Complex, evaluated with Diagnodent Pen and Diagnocam.

NCT ID: NCT05296213 Completed - Enamel Caries Clinical Trials

Medical Treatment of Early-Enamel Carious Lesion Using Different Remeneralizing Agents

Start date: December 1, 2019
Phase: N/A
Study type: Interventional

Medical Treatment of Early-Enamel Carious Lesion using Different Remeneralizing agents

NCT ID: NCT04756557 Completed - Dental Caries Clinical Trials

Caries-preventing Effect of a Hydroxyapatite-toothpaste in Adults

CA1
Start date: January 1, 2021
Phase: N/A
Study type: Interventional

Target question is as the following one: Does the daily use of a fluoride-free, microcrystalline hydroxyap-atite (HAP) - containing test toothpaste have a non-inferior caries preventing effect in the permanent dentition compared to the regular use of a fluoride control toothpaste (1450 ppm F-) with proven caries preventive efficacy (Walsh et al. 2019)? This multicenter, non-inferiority clinical trial, randomized, double-blind, active-controlled design, two-armed study evaluates the hypothesis that the home regular use of a toothpaste containing microcrystalline hydroxylapatite (HAP) (test toothpaste) provides a caries preventive effect in adults aged 18-45 comparable to the caries preventive effect provided by the regular use of a fluoridated tooth paste (1450 ppm -F) (control toothpaste) over observation periods of max. 18 months. Caries development will be assessed according to the clinical criteria of the Decay Missing Filling Surface Index (DMFS).

NCT ID: NCT04685889 Completed - Clinical trials for Molar Incisor Hypomineralization

Resin Infiltration Treatment for MIH

Start date: May 23, 2018
Phase: N/A
Study type: Interventional

The investigators aimed to evaluate changes in mineralisation degree, colour, and size of the lesion after Icon® in permanent teeth with MIH in 6 months.

NCT ID: NCT04155658 Completed - Enamel Caries Clinical Trials

Evaluation of Efficacy of Sodium Monofluorophosphate (SMPF) Toothpastes on Enamel Lesion Remineralisation

Start date: November 25, 2019
Phase: N/A
Study type: Interventional

Double-blind, randomized, 3 group in situ study to assess effect of three toothpastes on enamel remineralization, as measured by change in integrated mineral loss (∆∆Z). The study will examine the efficacy of an experimental sodium monofluorophosphate (SMFP) toothpaste, a standard SMFP toothpaste and a negative control toothpaste with no fluoride.

NCT ID: NCT03774498 Not yet recruiting - Enamel Caries Clinical Trials

Effect of Different Over-the-counter Toothpastes on Enamel Remineralization

RCT
Start date: January 1, 2019
Phase: N/A
Study type: Interventional

This study will be conducted to compare between recent over-the-counter toothpaste (Novamin & Fluoride) and regular over-the-counter toothpaste (Sodium Fluoride) in remineralization potential, so as to be able to know which of the toothpastes will have a better remineralization potential on demineralized enamel.