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Empyema clinical trials

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NCT ID: NCT06434324 Not yet recruiting - Pleural Infection Clinical Trials

Pleural Space Saline Irrigation in Addition to Standard Intrapleural Thrombolytic Therapy in Empyema/Complicated Parapneumonic Effusion

Start date: July 1, 2024
Phase: N/A
Study type: Interventional

The purpose of this study is to see if there is any benefit in adding saline irrigation through a chest tube to the standard course of treatment for people diagnosed or suspected of having a pleural space infection.

NCT ID: NCT06427538 Not yet recruiting - Pleural Infection Clinical Trials

Chest Drain Regular Flushing in Complicated Parapneumonic Effusions and Empyemas

RELIEF
Start date: June 1, 2024
Phase: N/A
Study type: Interventional

Infections of the pleural space are common, and patients require antibiotics and chest drain placement to evacuate the chest from the infected fluid. Chest drains can get blocked by the drainage fluid and material. For this reason, it is thought that flushing the chest drain with saline solution, can help maintain the patency of the tube. This proposed study will evaluate the impact of regular chest drain flushing on the length of time to chest tube removal and total hospitalization as well as improvement in chest imaging and the need for additional interventions on the infected space.

NCT ID: NCT06235359 Not yet recruiting - Empyema Clinical Trials

Is Intercostal Tube Enough in Management of Empyema

Start date: March 2024
Phase: N/A
Study type: Interventional

Is intercostal tube enough in management of empyema ?

NCT ID: NCT06132997 Not yet recruiting - Empyema Clinical Trials

Medical Thoracoscopy in Treatment Outcomes of Empyema Management

Start date: December 24, 2023
Phase: N/A
Study type: Interventional

To evaluate the efficacy of drainage achieved by thoracoscopy vs tube drainage alone. To compare clinical outcomes such as length of hospital stay, need for additional procedures, and treatment failure rates between the two drainage methods. To asses resolution of pleural infection and rates of fluid re-accumulation over follow-up. To compare safety profiles and complication rates of thoracoscopy versus tube drainage alone

NCT ID: NCT04695275 Not yet recruiting - Empyema Clinical Trials

Clinical Feature and Microbiology Characteristics of Empyema in Children

Start date: January 6, 2021
Phase:
Study type: Observational

The study is designed to clarify the clinical characteristics and reversion of children with empyema, observe the effect of streptococcus vaccine application on serotype of streptococcus, and to explore the susceptibility factors of streptococcus empyema in children in China.

NCT ID: NCT04177550 Not yet recruiting - Clinical trials for Empyema Thoracis in Children

Early Results of Empyema Thoracis Treatment in Children by Video-assisted Thoracoscopic Surgery

Start date: December 21, 2019
Phase:
Study type: Observational

The aim of study is to assess early results of Empyema Thoracis treatment in Children by Video-assisted Thoracoscopic Surgery

NCT ID: NCT03859206 Not yet recruiting - Empyema Clinical Trials

Medical Thoracoscopy Versus Tube Thoracostomy in Management of Empyema .

Start date: March 1, 2019
Phase: N/A
Study type: Interventional

Pleural empyema : is a collection of pus in the pleural cavity caused by microorganisms, usually bacteria.[1] Medical thoracoscopy has played a marginal role in the treatment of empyema for a long time, but has become more and more established in recent years. It can be per-formed in analgo-sedation in a bronchoscopy suite. It is minimally invasive and costs are much lower compared to surgical VATS. The diagnostic and therapeutic power seems to be comparable to VATS, since several studies show success rates with medical thoracoscopy between 73 and 100% (2, 3) .

NCT ID: NCT03716375 Not yet recruiting - Clinical trials for Complicated Pleural Effusion/ Empyema

Efficacy of Fibrinolytic Agents in Complicated Pleural Effusion

Start date: November 2018
Phase: N/A
Study type: Interventional

Intrapleural administration of fibrinolytic therapy, urokinase in parapneumonic effusion and empyema has been shown to decrease the need for surgical intervention and length of hospital stay. Pleural adhesions are easily formed in the early stages of empyema and the thickening of the pleural causes subsequent treatment difficulties. The goal of this study was to observe and compare the efficacy of treatment in empyema patients with urokinase and chest drainage or with chest drainage or with chest tube drainage alone so as to provide evidence for guiding clinical treatment.