Dyadic Neurofeedback for Emotion Regulation in Youth With Maternal Adversity

Emotional Dysfunction Clinical Trial

Official title: Dyadic Neurofeedback for Emotion Regulation in Youth With Maternal Adversity

Status Completed

Clinical Trial Summary

This study will examine the effect of a real-time functional magnetic resonance imaging (fMRI) dyadic neurofeedback protocol with mothers and their adolescent daughters. Mothers will view a moving bar showing their daughters' brain activity on a computer screen while talking to their daughters.

Clinical Trial Description

The current study will determine the effects of a real-time functional magnetic resonance imaging dyadic neurofeedback (rtfMRI-DNF) protocol that will train mothers with a history of adverse childhood experiences (ACEs) to regulate adolescents' activation in the anterior insular cortex (aIC) - a key brain region for ER. The proposed study will test the efficacy of this protocol to promote healthy ER-related neurodevelopment in adolescents with a maternal history of adversity. The proposed study will use DNF to provide neurofeedback from the adolescent's aIC to the parent as the parent and adolescent engage in an emotion discussion task together. Parents and adolescents (n=10 dyads) will communicate via microphones and noise-canceling headphones while the adolescent is undergoing fMRI scanning. Specific aims of the current study are: (1) to determine the brain response to aIC DNF adolescents, and (2) to determine effects of DNF on parenting behaviors. This study is significant because engaging with parents in DNF can promote positive ER development in adolescents at risk due to the intergenerational effects of ACEs. ;

Related Conditions & MeSH terms

• Emotional Dysfunction
• Stress, Psychological

• NCT number: NCT04964726
• Study type: Interventional
• Source: Oklahoma State University Center for Health Sciences
• Status: Completed
• Phase: N/A
• Start date: May 11, 2021
• Completion date: December 7, 2022