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Clinical Trial Details — Status: Recruiting

Administrative data

NCT number NCT06458920
Other study ID # 21-000929
Secondary ID R21HD108751
Status Recruiting
Phase N/A
First received
Last updated
Start date October 5, 2022
Est. completion date June 1, 2025

Study information

Verified date June 2024
Source University of California, Los Angeles
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

The goal of this project is to test whether regulating emotions with help from a friend is more effective and long-lasting in adolescents than regulating alone, and to characterize age-related differences in the neural mechanisms supporting social versus cognitive emotion regulation. Participants will complete a psychology experiment while undergoing fMRI scanning.


Description:

Participants will complete a novel paradigm during functional magnetic resonance imaging (fMRI) to examine whether adolescents (N = 50) and adults (N = 50) are more effective at down-regulating negative affect when a friend provides them with reinterpretations of negative stimuli (i.e. social reappraisal), as compared to when they reinterpret stimuli alone (i.e., cognitive reappraisal). Specifically, participants will look at pictures of upsetting events while undergoing fMRI scanning. For some pictures, they will be instructed to just look at the image. For other pictures, they will be told to listen to their friend's voice as their friend helps them to regulate their emotions. For other pictures, they will be told to regulate their emotions on their own. The primary comparison of interest is how participants regulate emotion on their own versus when their friend helps them.


Recruitment information / eligibility

Status Recruiting
Enrollment 100
Est. completion date June 1, 2025
Est. primary completion date June 1, 2025
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 13 Years to 25 Years
Eligibility Inclusion Criteria: - Adolescent participants must be 13-15 year of age - Adult participants must be 20-25 years of age - Proficient in English Exclusion Criteria: - Auditory, visual or cognitive impairment - Any health conditions that are contraindicated for MRI

Study Design


Related Conditions & MeSH terms


Intervention

Behavioral:
Social regulation
Participants will regulate emotion with the help of a friend
Cognitive regulation
Participants will regulate emotion on their own

Locations

Country Name City State
United States University of California, Los Angeles Los Angeles California

Sponsors (2)

Lead Sponsor Collaborator
University of California, Los Angeles Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Country where clinical trial is conducted

United States, 

Outcome

Type Measure Description Time frame Safety issue
Primary Negative affect Participant's self-reported negative affect on 1-4 scale (1=not bad at all, 4=very bad) during experiment 1 day
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