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Emergencies clinical trials

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NCT ID: NCT02601846 Completed - Pulmonary Embolism Clinical Trials

Age-adjusted D-dimer Cut-off to Rule Out Pulmonary Embolism in the Emergency Department : A Real Life Impact Study

RELAX-PE
Start date: November 2015
Phase:
Study type: Observational

A multicentre multinational prospective management outcome study has recently proven the safety of a diagnostic strategy combining clinical probability assessment with an age-adjusted D-dimer cut-off, defined as a value of (age x 10) in patients > 50 years, for ruling out PE in outpatients, with a very low likelihood of subsequent symptomatic VTE. Moreover, this study showed that such a strategy increased the diagnostic yield of D-dimers, as it allowed ruling out PE without further investigation in a significantly higher proportion of patients than when using standard cut-off, particularly so in patients 75 years or older. The objective of the present study is to confirm in a prospective cohort of "real life" patients the usefulness of the age-adjusted D-dimer cut-off to rule out PE in patients presenting to the emergency department with suspected PE.

NCT ID: NCT02586896 Completed - Opioid Dependence Clinical Trials

Comparing Interventions for Opioid Dependent Patients Presenting in Medical Emergency Departments

Start date: March 2016
Phase: N/A
Study type: Interventional

This study will compare the effects of brief strengths-based case management (SBCM) to the effects of screening, assessment and referral alone (SAR) in opioid-dependent patients. Participants meeting DSM-IV criteria for opioid dependence will be randomly assigned (150 per group) to receive 1) up to 6 sessions of SBCM; or 2) SAR. Follow-up assessments will be completed at 3 and 6 months, by staff who are blinded to treatment condition.

NCT ID: NCT02586779 Completed - Communication Clinical Trials

Effectiveness of WhatsApp (a Messenger Program) Usage in Emergency Department (ED)

Start date: October 2015
Phase: N/A
Study type: Interventional

Effective communication between consulting physicians and the emergency physicians is critical for patients in the emergency department. The aim of this study was to determinate effectiveness of whatsApp usage for communication between physicians.

NCT ID: NCT02584660 Completed - Pulmonary Embolism Clinical Trials

A Study of Rivaroxaban for Early Discharge of Low Risk Pulmonary Embolism From the Emergency Department

MERCURY PE
Start date: October 15, 2015
Phase: Phase 4
Study type: Interventional

The purpose of the study is to evaluate that low risk Pulmonary Embolism (PE) participants who are discharged from the Emergency Department (ED) to the home environment and treated with rivaroxaban as outpatients have fewer total days in the hospital for bleeding and/or venous thromboembolism (VTE) events through Day 30 compared to participants who are treated with initial hospitalization and standard-of-care.

NCT ID: NCT02582736 Completed - Clinical trials for Diabetes Mellitus, Type 2

Antipsychotics and Risk of Hyperglycemic Emergencies

Start date: April 2012
Phase: N/A
Study type: Observational

The purpose of this study is to determine whether the use of atypical antipsychotic medication increases the risk of hospitalization for a hyperglycemic emergency. The investigators will carry out separate population-based cohort studies using administrative health databases in eight jurisdictions in Canada and the UK. Cohort entry will be defined by the initiation of a new antipsychotic medication. Follow-up will continue until hospitalization for a hyperglycemic emergency or the end of 365 days. The results from the separate sites will be combined to provide an overall assessment of the risk of hyperglycemic emergencies among new users of various antipsychotic drugs.

NCT ID: NCT02576379 Completed - Thrombolysis Clinical Trials

The Impact of a Helicopter Emergency Medical System on Prognosis in Stroke Patients

Start date: January 2010
Phase: N/A
Study type: Observational [Patient Registry]

Stroke is a leading cause of death and disability, and 15 million people suffer a stroke each year; one-third die and one-third are left permanently disabled. Because the risk of stroke increases with age, it has been considered a disease of the elderly, but stroke also occurs in middle-aged people. Thrombolysis with tissue plasminogen activator (tPA) is the preferred choice of reperfusion therapy of ischemic stroke if performed within 4.5 hours from symptom onset. Time to thrombolysis is associated with improved outcome: the sooner the treatment, the less risk of serious - and possibly permanent - damage to the brain. Unfortunately, only a small fraction of stroke patients make it to thrombolysis within the 4.5-hour; one explanation may be system delays including prolonged transportation. In May 2010, the first physician-staffed Helicopter Emergency Medical Service (HEMS) was implemented in the Eastern part of Denmark. An observational study evaluating the short-term effects of HEMS implementation compared patients transported by conventional ground ambulance (Ground Emergency Medical Service (GEMS)) to patients transported by HEMS. Patients transported by helicopter had increased time to specialized care. However, both 30-day and 1-year mortality was slightly lower in patients transported by HEMS, although not significant, as was the degree of disability at three months measured by the modified Rankin Scale (mRS).

NCT ID: NCT02572232 Completed - Emergencies Clinical Trials

Supraglottic Airway Devices in Pediatric Difficult Airway Situations

Start date: September 1, 2016
Phase: N/A
Study type: Interventional

The purpose of the study is to compare three supraglottic airway devices (Combitube, Easytube, laryngeal mask airway) to endotracheal intubation in a simulated difficult airway scenario in a pediatric manikin.

NCT ID: NCT02572115 Completed - After-hours Care Clinical Trials

Differentiated Access to Out-of-hours Primary Care Through Emergency Access

Akutknappen
Start date: September 4, 2017
Phase: N/A
Study type: Interventional

The purpose of this randomized controlled trial is to test the use of an emergency button that allows patients to jump the telephone waiting line at the out-of-hours primary care in two regions in Denmark if they perceive their illness as acute and severe.

NCT ID: NCT02565680 Completed - Acute Urticaria Clinical Trials

Glucocorticoids With Antihistamines Versus Antihistamines in Acute Urticaria in Emergency

CAHISU
Start date: February 2012
Phase: Phase 2/Phase 3
Study type: Interventional

Acute urticaria is common and affected 12% of population. 400 patients come in department emergency of Toulouse each year and there aren't many studies in literature which evaluate the glucocorticoids treatment. The standard treatment of urticaria is antihistamines H1, but glucocorticoids treatment administered orally for short course would permit to increase quickly acute urticaria uncomplicated. Clinical trial, prospective randomized double blinded of adults with acute urticaria less 24 hours duration and no take treatment urticaria before.

NCT ID: NCT02559531 Completed - Triage Clinical Trials

Reliability of the Swiss Emergency Triage Scale (SETS®) Used by Emergency Medical Service (EMS) Providers

Start date: September 2015
Phase: N/A
Study type: Interventional

The Swiss Emergency Triage Scale (SETS) in used for triage in emergency departments in Switzerland, France and Belgium. No validated triage scale is actually used by Emergency Medical Service (EMS) providers. The objective of this project is to evaluate the reliability and performance of triage by EMS providers with the SETS.