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Emergencies clinical trials

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NCT ID: NCT03638921 Completed - Renal Colic Clinical Trials

35RC17_8826_NEPHROPAIN Phase APRES : Interest of the Equimolar Oxygen Nitride Mixture (MEOPA) in the Treatment of Pain in Patients Presenting to the Emergency Department for Suspected Renal Colic: a Study BEFORE AFTER

NEPHROPAIN
Start date: October 1, 2018
Phase: Phase 2
Study type: Interventional

MEOPA (Equimolar Oxygen-Nitrogen Protoxide Mix) is a gas used in emergencies for short-term painful acts. It is often very effective with an analgesic, anxiolytic and muscle relaxant action. It is often combined with other analgesic medicines. It has already been proven in emergency medicine for short-term pain and trauma. It seems that it could be used more particularly for pains of medical origin. A study has already proved its effectiveness in the treatment of migraines in emergencies. The first phase of the NEPHROPAIN study began in 2016 after a favorable opinion from the Regional Ethics Committee. NEPHROPAIN phase AVANT was a prospective non-interventional study on the use of analgesic drugs in nephritic colic in emergencies by Dr. Alexandre Tanneau. This study was conducted at the University Hospital of Rennes and included 60 patients admitted to the emergency department for suspected renal colic. It made it possible to recruit the control group of the NEPHROPAIN study. Its main objective was to describe the suspected population of renal colic in Rennes emergencies, to determine NEPHROPAIN's primary endpoint and the number of NEPHROPAIN needed subjects.

NCT ID: NCT03628820 Completed - Anxiety Clinical Trials

Canine Assisted Therapy to Reduce Emergency Care Provider Stress

CANINE II
Start date: May 17, 2018
Phase: N/A
Study type: Interventional

The main study hypothesis is that emergency healthcare workers on shift who interact for 5 min with a therapy dog and handler will have lower perceived and manifested stress response compared with use of a time out that includes voluntary use of a coloring mandalas. The work will also address two exploratory hypotheses: The first is that salivary cortisol will correlate significantly with perceived stress and will increase from beginning to end of shift, and that exposure to a therapy dog will blunt this increase. The second exploratory hypothesis states that participants who interact with a therapy dog will display more empathic behaviors.

NCT ID: NCT03617289 Completed - Renal Colic Clinical Trials

Efficacy of Magnesium Sulfate on Reducing Renal Colic in the Emergency Department

Start date: January 2016
Phase: N/A
Study type: Interventional

To determine if magnesium sulfate paired with an analgesic medication will improve patient pain from renal colic compared with analgesic alone.

NCT ID: NCT03615014 Completed - Clinical trials for Post Traumatic Stress Disorder

Predictive Factors of PTSD in Adults Admitted to an Emergency Service

ISSUE
Start date: February 11, 2019
Phase: N/A
Study type: Interventional

After trauma or stress factor like death exposition, serious injuries or sexual violence, some patients may develop stress reaction characterized by the presence of various symptoms among different categories (reviviscence, negative humor, dissociates symptoms, occasion, hypervigilance). In the month following trauma, the investigators speak of acute stress reaction (ASR) when symptoms are present during at least three days. If symptoms are present one month after trauma, then it is a post-traumatic stress disorder (PTSD). Among patients visiting emergency after latest trauma, quite a few is in acute stress reaction. However, this reaction is often incorrectly identified by healthcare team, due to lack of oriented medical examination, patients visiting about other complaints (pain, insomnia) and not expressing clearly the trauma context. Yet, it is know that acute stress reaction occurrence and existence of dissociate symptoms after trauma confrontation is considerably predictive of the eventual post-traumatic stress disorder occurrence. The identification of risk population of post-traumatic stress disorder is not the subject of any particular structured procedure in emergency services while early care of these patients may allow limiting post-traumatic stress disorder occurrence and associate consequences. Previous works on the subject having exclusively targeted some trauma subgroups or some predictive factors subtypes, investigators propose here biopsychosocial global approach that can weight the impact of each parameters. In this study, investigators aim at determining predictive biopsychosocial factors of the post-traumatic stress disorder occurrence at 3 months in patients visiting emergency after latest trauma (less than one month old) and identified as "high-risk" to develop post-traumatic stress disorder (moderate or high).

NCT ID: NCT03614494 Completed - Clinical trials for Emergency Contraception

Piroxicam and Levonorgestrel Co-treatment for Emergency Contraception

Start date: August 20, 2018
Phase: Phase 2/Phase 3
Study type: Interventional

This is a randomised controlled trial aimed at comparing the efficacy of levonorgestrel (LNG) co-administered with piroxicam or placebo for oral emergency contraception (EC). Piroxicam is a non-steroidal anti-inflammatory drug (NSAID) commonly used as a pain-killer in inflammatory conditions. Efficacy will be measured as the percentage of pregnancies prevented.

NCT ID: NCT03611413 Completed - Colon Perforation Clinical Trials

Feasibility and Effects of an Enhanced Recovery vs Conventional Care After Emergency Colon Surgery for Patients With Left Colon Perforation.

Start date: March 1, 2014
Phase:
Study type: Observational

A study was designed with a prospective cohort of all patients undergoing urgent surgery for left colon perforation between March 2014 and June 2017 who were treated according to a specific ERAS programme (ERAS group/29 patients). This group was compared with a historic case-matched control group with conventional care (CC group/21 patients). The main endpoints were postoperative 30-day morbidity, length of postoperative hospital stay, rate of readmission within 30 days, and mortality. The inclusion criteria were patients over 18 years old with a low-moderate risk of mortality according to a Peritonitis Severity Score (PSS) between 6-11 points.

NCT ID: NCT03609281 Completed - Clinical trials for Cesarean Section; Dehiscence

Cesarean Scar Characteristics After Scheduled and Emergency Cesarean Deliveries

Start date: August 1, 2018
Phase:
Study type: Observational [Patient Registry]

This study was designed to evaluate the scar characteristics following scheduled and emergency cesarean deliveries.

NCT ID: NCT03602183 Completed - Cardiac Arrest Clinical Trials

Pediatric Intubation During Emergency Conditions

Start date: July 27, 2018
Phase: N/A
Study type: Interventional

The effectiveness of endotracheal intubation in pre-hospital conditions is insufficient - especially in the context of pediatric patients. Anatomical differences in pediatric patients compared to adults: a relative larger tongue, a larger and more flabby epiglottis - located more cephalously - that make intubation is more difficult than for adults. Also, higher oxygen metabolism requires the immediate response of medical personnel to children in case of need to protect the airways and support breath.

NCT ID: NCT03601676 Completed - Pulmonary Embolism Clinical Trials

Electronic Support for Pulmonary Embolism Emergency Disposition

eSPEED
Start date: January 1, 2015
Phase: N/A
Study type: Interventional

To evaluate the impact of an integrated electronic clinical decision support system to facilitate risk stratification and site-of-care decision-making for patients with acute pulmonary embolism.

NCT ID: NCT03595527 Completed - Hiv Clinical Trials

Universal HIV Screening and Targeted HCV Screening in Emergency Department

Start date: July 10, 2018
Phase: N/A
Study type: Interventional

Cross-sectional study of patients consulting in the emergency room of the Centre hospitalier de l'Université de Montréal (CHUM), to assess the implementation of an "opt-out" screening program for HIV and HCV and prospective follow-up for 3 months of positive cases.