Effect of Dilatation and Curettage on the Endometrial Receptivity

Embryo Implantation Clinical Trial

Official title:

Effect of Dilatation and Curettage on the Endometrial Receptivity and Pregnancy Outcome in Patients With Recurrent Implantation Failure

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03485235
• Other study ID #: AS1764
• Status: Completed
• Phase: N/A
• Start date: March 31, 2018
• Est. completion date: December 10, 2019

Study information

• Verified date: January 2020
• Source: Ain Shams University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Effect of dilatation and curettage on the endometrial receptivity and pregnancy outcome in patients with recurrent implantation failure

Recruitment information / eligibility

• Status: Completed
• Enrollment: 160
• Est. completion date: December 10, 2019
• Est. primary completion date: November 1, 2019
• Accepts healthy volunteers: No
• Gender: Female
• Age group: 25 Years to 35 Years

Eligibility

Inclusion Criteria:

1. All the patients had at least 3 failed trials of IVF-ET with day 5 fresh blastocyst transferred

2. At least 10 high-grade embryos were obtained in the previous trials

3. Level of AMH more than or equal 1.1 ng/ml.

4. Age: Less than or equal to 35 years

Exclusion Criteria:

1. Patients with uterine pathology e.g. myoma , Asherman syndrome, Septum ,adenomyosis

2. Hydrosalpinx

3. Endometriosis

4. patients with diagnosed autoimmune diseases affecting pregnancy e.g. S.L.E.

Related Conditions & MeSH terms

• Aneurysm
• Embryo Implantation

Intervention

Procedure:
• D&C
Dilatation and curettage
• ICSI
Intra Cytoplasmic Sperm Injection

Locations

Country	Name	City	State
Egypt	Ain Shams University Maternity Hospital	Cairo

Sponsors (1)

Lead Sponsor	Collaborator
Ain Shams University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Live Birth Rate		9 months