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Clinical Trial Summary

This is a randomized, double-blinded, cross-over pilot study comparing the effects of ingesting high molecular weight oats containing β-glucan in reducing blood pressure.

Clinical Trial Description

The pilot study will consist of 2 study periods: one treatment period and one control period. The treatment period will provide food products made from oats, containing a total of 4 grams per day high molecular weight (HMW) oat β-glucan, whereas, the control period will provide food products made primarily from wheat with no β-glucan. The study will be located at the Chronic Disease Innovation Centre in Seven Oaks General Hospital, Winnipeg, Canada. The primary outcome of this study is the effect of ingestion of HMW oat β-glucan in reducing ambulatory blood pressure. Participants will be asked to wear an ambulatory blood pressure monitor for 24 hours per day for 3 consecutive days at the beginning and end of each treatment period. This device automatically measures blood pressure every 15-30 minutes during the day and 30 to 60 minutes during the evening. The study has been designed to be conducted virtually. Participants will consent to receive both treatment and control over two 4-week periods online. The participants will be randomized to 2 groups, at 4 weeks and at 12 weeks with a 4 week wash out period in between. ;

Study Design

Related Conditions & MeSH terms

NCT number NCT05029427
Study type Interventional
Source University of Manitoba
Contact Rebecca Mollard, PhD
Phone 204-631-3834
Email [email protected]
Status Not yet recruiting
Phase N/A
Start date October 1, 2021
Completion date October 31, 2022

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