Effects of Different Forms of Fatigue on Double-Task Performance in the Elderly

Elderly Clinical Trial

Official title:

Effects of Different Forms of Fatigue on Double-Task Performance in the Elderly

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04806022
• Other study ID #: 21-PP-02
• Status: Completed
• Phase: N/A
• Start date: January 19, 2022
• Est. completion date: October 6, 2022

Study information

• Verified date: October 2022
• Source: Centre Hospitalier Universitaire de Nice
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The dual task (walking and cognitive task at the same time) is increasingly used in geriatrics in protocols for detecting people who are falling and/or for highlighting cognitive disorders. However, frail elderly people tend to get tired quickly and a lack of awareness of the effects of fatigue on dual-task performance could alter the diagnosis.

There are two types of fatigue: mental fatigue and peripheral muscle fatigue. Each participant will do both types of fatigue over 2 appointments spaced by 7 days so that the subject can recover from induced fatigue. The sequence of fatigue tasks will be randomized.

At the first appointment (day 0):

1. Pre-fatigue assessment :

• The subject must walk on 10m with round trip for 1min.

• the subject must do the arithmetic count of 3 in 3

• Then comes the evaluation in double task (walking and counting at once for 1min). The subject must walk on 10m with round trip for 1min by doing the arithmetic count of 3 in 3 at the same time.

2. mental fatigue task or muscle fatigue task (randomized)

3. post-fatigue assessment (the same as pre-fatigue assessment)

7 resting days

Second appointment (day 7)

1. Pre-fatigue assessment :

• The subject must walk on 10m with round trip for 1min.

• the subject must do the arithmetic count of 3 in 3

• Then comes the evaluation in double task (walking and counting at once for 1min). The subject must walk on 10m with round trip for 1min by doing the arithmetic count of 3 in 3 at the same time.

2. mental fatigue task or muscle fatigue task (randomized)

3. post-fatigue assessment (the same as pre-fatigue assessment)

Recruitment information / eligibility

• Status: Completed
• Enrollment: 66
• Est. completion date: October 6, 2022
• Est. primary completion date: September 30, 2022
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 20 Years to 90 Years

Eligibility

Young group

Inclusion Criteria:

• 20 to 40 years old

Exclusion Criteria:

• psychiatric disorders

• Severe hearing or vision loss

• Motor or sensory disability that may interfere with test completion

Old group

Inclusion Criteria:

• 65 to 90 years old

• less than 3 Fried's criteria of fragility

• walking ability without technical assistance (at least 10m).

Exclusion Criteria:

• psychiatric disorders

• Severe hearing or vision loss

• Motor or sensory disability that may interfere with test completion

Old frail group

Inclusion Criteria:

• 65 to 90 years old

• 3 or more Fried's criteria of fragility

• walking ability without technical assistance (at least 10m).

Exclusion Criteria:

• psychiatric disorders

• Severe hearing or vision loss

• Motor or sensory disability that may interfere with test completion

Related Conditions & MeSH terms

• Elderly
• Fatigue

Intervention

Other:
• Fatigability assessment
Each participant will do both types of fatigue over 2 appointments spaced by 7 days so that the subject can recover from induced fatigue. The sequence of fatigue tasks will be randomized.

Locations

Country	Name	City	State
France	CHU de Nice	Nice

Sponsors (1)

Lead Sponsor	Collaborator
Centre Hospitalier Universitaire de Nice

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Dual task performance after muscular fatigue	Dual task performance (DTEspeed motor performance; DTEcog cognitive performance) will be compared before and after a protocol of peripheral mental and muscular fatigue.; For Dual Task Performance, the cognitive task performance (maximum count count - error count) performed alone (single ST task) and performed while walking (double ST task) will be compared.	at inclusion (day 0)
Primary	Dual task performance after cognitive fatigue	Dual task performance (DTEspeed motor performance; DTEcog cognitive performance) will be compared before and after a protocol of peripheral mental and muscular fatigue.; For Dual Task Performance, the cognitive task performance (maximum count count - error count) performed alone (single ST task) and performed while walking (double ST task) will be compared.	at day 7