HIT in the Healthy Elderly Population

Elderly Clinical Trial

— HIT  

Official title:

Determining the Effectiveness of a High Intensity Interval Training Exercise Programme in the Healthy, Elderly Population

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02167191
• Other study ID #: HIT
• Status: Completed
• Phase: N/A
• First received: June 16, 2014
• Last updated: September 30, 2015
• Start date: February 2014
• Est. completion date: August 2014

Study information

• Verified date: September 2015
• Source: University of Nottingham
• Contact: n/a
• Is FDA regulated: No
• Health authority: United Kingdom: Research Ethics Committee
• Study type: Interventional

Clinical Trial Summary

It is widely known that exercise improves general fitness and that fitter patients recover more easily from illness and surgery. Conversely, unfit patients have a significantly higher morbidity and mortality after surgery and a longer inpatient stay. This will become increasingly important in an aging population as baseline fitness generally declines with age.

One method of improving cardiovascular fitness is by using low intensity endurance training programmes, a disadvantage of these it that they can take several months to show improvement. High intensity interval training (HIT) programmes that use short episodes of high intensity exercise have also been shown to improve fitness. These HIT programmes have also shown improvement in functional capacity and quality of life in patients with chronic disease. An advantage of HIT is that improvements in fitness may occur in a shorter time than traditional endurance training. It is also known that HIT can give superior gains over endurance training.

The primary aim of this study is to determine whether an improvement in aerobic fitness, as judged by a 2ml/kg/min increase in VO2peak, can be achieved within 31 days via a HIT programme, in a group of healthy elderly volunteers.

As a secondary aim we will assess whether this programme would be acceptable to the group studied, through determination of subject compliance and adherence to the training programme.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 24
• Est. completion date: August 2014
• Est. primary completion date: July 2014
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 60 Years to 75 Years

Eligibility

Inclusion Criteria:

• Good health

• Male and female

• 60 -75 years old

Exclusion Criteria:

• Uncontrolled hypertension (BP > 140/100)

• Angina

• Heart failure (NYHA class III/IV)

• Cardiac arrthymias

• Right to left cardiac shunt

• Recent cardiac event

• Previous stroke/TIA

• Aneurysm (large vessel or intracranial)

• Severe respiratory disease including pulmonary hypertension

• COPD/asthma with an FEV1 less than 1.5 l

• Inclusion into any other research study in the last three months which involved:

taking a drug; being paid a disturbance allowance; having an invasive procedure or exposure to ionising radiation

Study Design

Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Basic Science

Related Conditions & MeSH terms

• Elderly
• Interval Training
• Pre Operative Exercise
• Prehabilitation

Intervention

Behavioral:
• HIT
12 sessions of HIT exercise in 31 days on a stationary cycle ergometer

Locations

Country	Name	City	State
United Kingdom	University of Nottingham	Derby	Derbyshire

Sponsors (1)

Lead Sponsor	Collaborator
University of Nottingham

Country where clinical trial is conducted

United Kingdom, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	VO2 peak		31 days	No