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Study on the Correlation Between NAT2(N-acetyltransferase2) Gene Polymorphism and CrCl(Creatine Clreance) and the Efficacy and Safety of Levosimendan in Patients With Severe Heart Failure

Heart Failure Clinical Trial

Official title:
Study on the Correlation Between NAT2(N-acetyltransferase2) Gene Polymorphism and CrCl(Creatine Clreance) and the Efficacy and Safety of Levosimendan in Patients With Severe Heart Failure

Clinical Trial Summary

1. To evaluate the efficacy and safety of levosimendan in the treatment of heart failure ; 2. Guide patients to apply levosimendan individually and establish a dose adjustment program.

Clinical Trial Description

The efficacy and safety of levosimendan in Chinese patients with different acetylmetabolites and CrCl(Creatine clreance) were re-evaluated after marketing. The population pharmacokinetics of different populations was studied, and the patients were guided to apply levosimendan individually and establish a dose adjustment program. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05913271
Study type Observational [Patient Registry]
Source Qianfoshan Hospital
Contact Yi Han, doctorate
Phone 15552565120
Email 15552565120@163.com
Status Recruiting
Phase
Start date May 30, 2023
Completion date May 30, 2025
View Details
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