Post-operative Pain Reduction

Effects of the Elements Clinical Trial

Official title:

Post-operative Pain Reduction After Application of Three Intracanal Medicament Within Necrotic Root Canals and Pulp

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT04338633
• Other study ID #: 314
• Status: Recruiting
• Phase: N/A
• Start date: April 2020
• Est. completion date: November 2020

Study information

• Verified date: April 2020
• Source: Minia University
• Contact: Mohamed Salah Hegazi
• Phone: +201224014179
• Email: mshegazi2006[@]gmail.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Recruited patients with necrotic pulp after application of conventional calcium hydroxide paste are assigned to group, Calcium hydroxide nanoparticle group and Combined Calcium hydroxide with silver nanoparticle group and record postoperative pain afterwards.

Description:

The investigator will recruit patients who are found eligible to the criteria, conventional calcium hydroxide paste , Calcium hydroxide nanoparticle and Combined Calcium hydroxide with silver nanoparticle . After 48 hours, patients will be randomly assigned to removal of intracanal medication

After the visit, patients will be asked to record post operative pain by Numerical Rating Scale)in a given sheet

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 30
• Est. completion date: November 2020
• Est. primary completion date: November 2020
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 25 Years to 50 Years

Eligibility

Inclusion Criteria:

• • Medically free patients.

• Patient's age between 25-50 years.

• Sex includes both male and female.

• Radiographic evidence of a periapical radiolucent lesion associated with tooth.

• Necrotic pulp as indicated by thermal pulp testing.

• No history of previous endodontic treatment of the tooth.

Exclusion Criteria:

• • Teeth with unfavorable conditions for rubber-dam application.

• Teeth with acute periapical abscesses swelling.

• Medically compromised patients.

• Immature teeth with open apices.

• Multi rooted teeth.

• Pregnant women.

Related Conditions & MeSH terms

• Effects of the Elements
• Pain, Postoperative

Intervention

Drug:
• Conventional calcium hydroxide paste
Conventional calcium hydroxide paste (Ultracal) will be removed in second visit.
• Calcium hydroxide nanoparticle
Calcium hydroxide nanoparticle. manufactured in NanoTech. institute, will be removed in second visit.
• Combined Calcium hydroxide with silver nanoparticle
Combined Calcium hydroxide with silver nanoparticle will be removed in second visit.

Locations

Country	Name	City	State
Egypt	Faculty of Dentistry, Minia University	Minya

Sponsors (1)

Lead Sponsor	Collaborator
Minia University

Country where clinical trial is conducted

Egypt, 

References & Publications (1)

Singh RD, Khatter R, Bal RK, Bal CS. Intracanal medications versus placebo in reducing postoperative endodontic pain--a double-blind randomized clinical trial. Braz Dent J. 2013;24(1):25-9. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	change in post operative pain (Visual Analogue Scale)	Numerical (0-10)	Intrappointment at 4,24,48,72 and 96 hours ]