Effect on Cerebrovascular Reactivity Clinical Trial
Official title:
A Randomised Trial of Effect of Deep-fried Chocolate Bar and Porridge Upon Cerebrovascular Reactivity in Healthy Adult Volunteers
The deep fried chocolate bar is a snack that the international community strongly associates
with Scotland. It has previously been cited as being "a symbol of all that is wrong with the
high-fat, high-sugar Scottish diet". Despite the snack's reputation, no medical research has
been performed to examine the effects of consuming a deep fried chocolate bar on the human
body.
In contrast to the deep fried chocolate bar, porridge has been shown to reduce the risk of
cardiovascular disease, but its effect on cerebral blood flow has yet to be directly
assessed.
This study will focus on the potential (patho)physiological cerebrovascular effects of the
deep fried chocolate bar and porridge. The research question to be addressed in this study
is "Does eating a deep fried chocolate bar or bowl of porridge induce changes in cerebral
blood flow and cereborvascular reactivity in healthy adults?"
To assess the acute effects on eating either food on blood flow through the largest artery
in the brain, the investigators will give healthy volunteers one regular-sized deep-fried
chocolate bar or a bowl of porridge. Blood flow through the largest artery in the brain will
be assessed using simple ultrasounds tests. The investigators aim to recruit 24 volunterrs
who will visit twice, consuming a different food on each visit.
n/a
Allocation: Randomized, Intervention Model: Crossover Assignment, Masking: Open Label, Primary Purpose: Basic Science