Effect of Hypophosphatemia on Septic Patients Clinical Trial
Official title:
Hypophosphatemia Deleteriously Affects Outcome of Septic Shock Patients Admitted to ICU
Patients with severe sepsis/septic shock complicated by hypophosphatemia are at high risk of developing morbidities other than that underlying sepsis and more vulnerable to higher mortality rate. Thus, the current study hypothesized that diagnosis and management of hypophosphatemia may be advantageous for reduction of morbidity and mortality rates of septic patients admitted to ICU
The current study was started since June 2018 till Jan 2020 after approval of the study
protocol by the Local Ethical Committee. The study intended to include all patients admitted
to ICU with or developed severe sepsis or septic shock within 24-hr after admission to ICU.
All patients admitted to ICU were eligible to evaluation for demographic and clinical data
including hemodynamic data. Disease severity and its impact on body organs were evaluated
using acute physiology and chronic health evaluation II score (APACHE II) (20) and SOFA (18)
scores. Exclusion criteria included maintenance on immunodepressent therapy for any
indication, severe hemorrhagic shock, pregnancy and refusal of nearest relative to sign the
written concept for study participation. Children and adulthoods younger than 18 years and
patients who were expected to die were also excluded from the study.
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