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Edentulous Mouth clinical trials

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NCT ID: NCT05441527 Enrolling by invitation - Edentulous Jaw Clinical Trials

Use of Two Dissolvable Therapeutics Under Removable Partial Dentures

Start date: June 30, 2022
Phase: N/A
Study type: Interventional

Older removable denture wearing adults suffer from a complex set of oral health challenges, with relatively few solutions identified at this time. This is substantiated by statistics concerning the geriatric population on the correlation of poor oral health and the degradation of an individual's overall quality of life. The most recent National Health and Nutrition Examination Survey data found that 1 in 8 U.S. adults over the age of 65 are completely edentulous. A shift from complete edentulism to partial edentulism was also seen in this survey data, as the average individual over 65 had only 21 teeth remaining. Thus, partial edentulism remains a significant burden on seniors as well. Clearly, there exists both a great need and desire for improved implementation of proven oral-health strategies among this population, as well as the development of new preventive interventions and minimally invasive treatment strategies beyond traditional denture adhesive products. This proposed clinical trial intends to investigate two such potential treatment aids. In follow-up from our recent pilot study investigating MI Paste's application on the intaglio of complete dentures, in which our current findings have shown that the use of MI Paste can predictably increase the buffering capacity of a patient's saliva, our current proposal targets to further increase the study's sample size to improve the statistical power regarding subjective patient reports. The primary aims of this proposed study are to collect further data on how MI Paste affects patients' subjective evaluations of the comfort and retention of their denture, as well as dry mouth symptoms in patients reporting xerostomia. Furthermore, this study will include a second therapeutic intervention, Biotene Dry Mouth Gel (OTC), which will provide an additional contrast variable involving patient preferences regarding therapeutics under their removable prostheses. We hypothesize that the use of both therapeutics underneath removable dentures will provide added retention and stability to the prosthesis on patient reports, further coinciding with improved evaluations of comfort and function. Additionally, we hypothesize that the subjective improvements in patients self-reporting xerostomia will be of a statistically greater magnitude than those noticed by patients with normal salivary function, as xerostomia has been associated with increased denture discomfort in past literature.

NCT ID: NCT05375045 Recruiting - Edentulous Mouth Clinical Trials

Real-life Evaluation of the Safety and Performance of EUROTEKNIKA Dental Implants

Start date: March 25, 2022
Phase:
Study type: Observational

Real-life evaluation of the safety and performance of EUROTEKNIKA dental implants

NCT ID: NCT04984499 Active, not recruiting - Edentulous Mouth Clinical Trials

In Vivo Clinical Investigation of the Safety and Performance of Dental Implants TBR® Tissue Level Z1

Z1
Start date: September 23, 2021
Phase:
Study type: Observational

Partial or total edentulousness has a significant impact on quality of life both functionally and aesthetically. TBR® Tissue Level Z1 Implants allow the patient to prevent bone resorption and maintain facial tissue and musculature support. At the functional level, the patient who benefits from implant treatment regains normal masticatory function with all the benefits on the quality of life that this can bring him. Due to the osseointegration of the implant and the biocompatibility of the materials used, the implant treatment remains effective in the long term and makes it possible to maintain the aesthetics of the smile.

NCT ID: NCT04853459 Completed - Edentulous Mouth Clinical Trials

A Technique for Border Molding in Complete Dentures Using Light-Cured

Start date: September 15, 2021
Phase: N/A
Study type: Interventional

Since the teeth loss leads to disability & impairment, and teeth restoration lead to improvement in the life quality throughout the oral health improvement. The acceptable function of a complete denture on great extent depends on impression technique which includes the maximum coverage of denture supporting areas and making a combination of managing movable soft tissues along with different kinds of impression materials and techniques for accurate reproduction of oral foundation. Border molding considered to be as an important step in the in complete denture fabrication, since the retention of complete dentures depend on several factors, as the biological, physical and mechanical, these factors could be achieved by mean of an accurate border molding followed by an accurate final impression. The border molding technique is the shaping of the border areas of a custom impression tray by manual or functional manipulation of the tissue adjacent to the borders in order to duplicate the size and contour of the vestibule resulting in maintains of the peripheral seal during function. This property causes the border molding process to require twenty-four insertions, namely eight in the maxilla and sixteen in the mandible causing long working time and discomfort in patients. Hence, the material used for this technique should provide optimum working time, have adequate body, and permit the correction of border moulding by additions. However additions if made to a single step border moulded material would again introduce all the disadvantages that are associated with sectional moulding Single-step border molding is considerably more straightforward than sectional border molding owing to the reduced number of tray insertions. This technique is usually used with elastomeric impression materials, which may not provide sufficient time to mold and record the peripheral tissues of the denture bearing area. The present technique uses light polymerizing tray material for molding tray borders, offering extended working time. This is advantageous for operators with less experience, such as dental school students. Furthermore, correction of border molding is possible with the addition of new material. The technique uses materials that are readily available,and no special armamentarium is required.

NCT ID: NCT04760457 Completed - Edentulous Mouth Clinical Trials

Mandibular Overdentures Retained by Mini Implants: a Clinical Trial Comparing Different Surgical and Loading Protocols

SMIS
Start date: March 1, 2021
Phase: N/A
Study type: Interventional

This study aims to test the combined effects of different loading protocols and surgical approaches on clinical and patient-reported outcome measures (PROMs) following the use of four mini implants for mandibular overdenture retention. The main study hypotheses are: 1. There are significant improvements in PROMs following implant intervention compared to baseline measures; 2. Immediately loaded mini implants have similar failure rates compared to mini implants receiving a delayed 6-week protocol. 3. Flapless surgery has similar post-insertion outcomes compared to flapped surgery.

NCT ID: NCT04569929 Completed - Edentulous Mouth Clinical Trials

3D-printed Implant Overdentures

Start date: January 1, 2019
Phase: N/A
Study type: Interventional

A randomized clinical trial (RCT) was designed. Fourteen completely edentulous participants were randomly allocated into two equal groups. All participants received two implants in the inter-foraminal area with ball attachments. Participants in the control group were rehabilitated with conventionally manufactured Polymethyl Methacrylate (PMMA) maxillary complete denture and mandibular implant overdentures while participants in intervention group received digital light processed (DLP)-printed photo-polymerizable PMMA Nextdent maxillary complete denture and mandibular implant overdentures. Follow-up appointments were scheduled at 3,6, and 12 months where data of Oral Health Impact Profile 19(OHIPEDENT19) was used to assess the OHRQoL (oral health related quality of life). In addition, denture retention was measured using digital force gauge device. Data were collected and statistically analyzed.

NCT ID: NCT04475913 Completed - Edentulous Mouth Clinical Trials

Digital vs Analog Impression in Cases of All-on-4 - Prosthesis

Start date: July 11, 2018
Phase: N/A
Study type: Interventional

Fifty six patients were randomly enrolled in the study. Participants were randomly stratified into two control groups and two test groups, from which conventional pick up and digital impressions were made respectively. Patients of group 1 (CIG Axial) and 3 (DIG Axial) received 4 axial implants whereas, group 2 patients (CIG Tilted), and group 4 (DIG Tilted) received two anterior axial implants and two distal tilted implants. All participants received hybrid dentures. Bone loss, implant loss, maintenance of prosthesis were evaluated at 6m,12m, and 24 months follow up period.

NCT ID: NCT04366895 Completed - Edentulous Mouth Clinical Trials

3D -Printed Single Implant Overdentures

Start date: January 20, 2021
Phase: N/A
Study type: Interventional

A randomized clinical trial (RCT) was designed. The participants were randomly allocated into either of the two groups intervention or control group each of 14 participants. Participants in control group (Group-A) received conventional manufactured implant overdenture while participants in intervention group (Group-B) received CAD-CAM manufactured implant overdenture.

NCT ID: NCT03691285 Completed - Edentulous Mouth Clinical Trials

Mandibular Overdenture Retained by 1 or 2 Implants: a Cost-effectiveness Analysis

IOD1-2
Start date: April 9, 2017
Phase: N/A
Study type: Interventional

The aim of this study is to assess the cost-effectiveness of the mandibular overdenture retained by one and two implants, based on a randomized clinical trial.

NCT ID: NCT03675594 Not yet recruiting - Edentulous Mouth Clinical Trials

Retention of Computer Aided Design and Computer Aided Manufacturing Titanium Versus Co/Cr Single Dentures.

Start date: December 1, 2018
Phase: N/A
Study type: Interventional

- Steps in short: Undergoing the conventional steps of maxillary single denture construction till the step of framework construction that will be designed and constructed using CAD/CAM after optical scanning of the master cast ( 2 frameworks to cover the palate and crest of the ridge : one made of titanium and the other made of cobalt/chromium) then conventional steps will be undergone including bite, Try-in and delivery ending by measuring the denture retention. - Number of visits & follow up period : Visits: will be 5-6 visits for each patient. Follow up period: 6.5 months (immediately post-insertion then after 1 week then after 3 months for the first type then 2 weeks washout period and the same for the second type)