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Echocardiography clinical trials

View clinical trials related to Echocardiography.

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NCT ID: NCT05741229 Recruiting - Respiratory Disease Clinical Trials

The Effect Of Nebulizied Nitroglycerin As An Adjuvant Therapy For Persistent Pulmonary Hypertension Of Newborns

Start date: July 20, 2023
Phase: N/A
Study type: Interventional

This aim of the study is to evaluate the effect of nebulized nitroglycerin on echocardiographic (biventricular function, pulmonary artery pressure, PDA and PFO shunting and tissue doppler imaging) and clinical parameters (Oxygen saturation index, heart rate, blood pressure, mean airway pressure, ventilation setting) in patients with PPHN.

NCT ID: NCT05726578 Not yet recruiting - Echocardiography Clinical Trials

Integrated Echocardiography and Chest Ultrasound Assessment of Lung Recruitment in Preterm Infants

Start date: March 1, 2024
Phase: N/A
Study type: Interventional

The primary aim of this work is to evaluate the role of high frequency oscillatory ventilation (HFOV) in recruitment of lung in preterm newborns 32 to 37 weeks gestational age with moderate to severe respiratory distress. The secondary aim is to evaluate the role of chest ultrasound in monitoring of lung recruitment in comparison to routine chest x ray in those babies. Also cardiac hemodynamics will be assesed using functional echocardiography.

NCT ID: NCT05706428 Completed - Clinical trials for Hemodynamic Instability

Cardiorespiratory Effects of Nasal High Frequency Ventilation in Neonates

Start date: February 1, 2023
Phase: N/A
Study type: Interventional

The aim of the present work is to study the cardio-respiratory effects of non-invasive ventilation (nasal high-frequency ventilation and nasal CPAP) as an initial therapy of respiratory distress in moderate and late preterm infants as regard: I. Primary outcomes: - Duration of the non- invasive respiratory support. - Need of invasive ventilation in the first 72 hours. - Short-term complications such as air leak syndromes, pulmonary hemorrhage, intraventricular hemorrhage, and nasal trauma. II. Secondary outcomes: - Need for surfactant administration. - Days on invasive mechanical ventilation. - Days on supplemental oxygen. - Duration of hospital stay. - Mortality rate. III. Hemodynamic changes during the period of non-invasive ventilation.

NCT ID: NCT05633732 Recruiting - Echocardiography Clinical Trials

Developing Echocardiography Image Quality Management System Based on Deep Learning

Start date: December 30, 2022
Phase:
Study type: Observational

To develop an echocardiography image quality management system based on deep learning to achieve objective and accurate automatic echocardiography image quality control. A total of 2000 patients performing transthoracic echocardiography were prospectively enrolled in the Department of Ultrasound Medicine of the Affiliated Drum Tower Hospital with Medical School of Nanjing University. The data of 8 TTE view segmentations were collected, including the views of the parasternal long axis of the left ventricle (PLAX_LV), parasternal short axis of the large vessel level (PSAX_GV), parasternal short axis of the mitral valve level (PSAX_MV), parasternal short axis of the papillary muscle level (PSAX_PM), parasternal short axis of the apical level (PSAX_AP), apical four cavity (A4C), apical three cavity (A3C), apical two cavity (A2C). The data of 1500 patients were used as the training set, and the rest were used as the validation set. These video data were classified into corresponding view segmentations and analyzed by the Video Swin Transformed Model. Then, the scoring module of different view segmentations combined key frame extraction, image segmentation, video target recognition and video classification model were established. At the same time, the scores achieved by the automatic echocardiography image assessment system were compared with the artificial score. By constantly correcting and learning and eventually building an primary automated grading system. At last, the automatic echocardiography image assessment system was constructed and performed on the rest 500 patients.

NCT ID: NCT05624619 Recruiting - Sepsis Clinical Trials

The Diagnostic and Prognostic Value of Speckle Tracking Imaging in Septic Cardiomyopathy

Start date: December 18, 2022
Phase:
Study type: Observational

The aim of this study is to explore if STI technology, especially TMAD, plays an important role in evaluating left ventricular longitudinal systolic function and discriminating SICM in patients with sepsis. The investigators also intend to prove that TMAD may have predictive value in patients with sepsis, which is worthy of in-depth study to find strong evidence-based medical evidence for subsequent clinical practical applications.

NCT ID: NCT05558774 Recruiting - Atrial Fibrillation Clinical Trials

Long-term Outcomes After Percutaneous Closure of PFO

Start date: July 11, 2022
Phase:
Study type: Observational [Patient Registry]

International medical centre Medicor from Slovenia has reported 306 successful percutaneous closures of patent foramen ovale (PFO) from October 2006 till June 2022. The investigators are going to follow-up the participants clinically and with contrast transthoracic echocardiography (TTE) to define the percentage of functional percutaneous closure. The latter is defined with the number (ten or less) of contrast-bubbles in the left atrium during Valsalva maneuver and contrast (agitated saline) application. The clinical follow-up will show the recurrence of embolic events (cerebrovascular insults, transient ischemic attacks) after percutaneous closure. In addition all of the participants are going to be screened for atrial fibrillation. The patients with moderate residual shunts (more than ten bubbles in the left atrium) will then according to the protocol have a transesophageal echocardiogram (TEE) to show the eventual mechanism of the shunt. If the TEE will not show any signs of a residual shunt, the patients will undergo a computed tomography angiogram (CTA) of the pulmonary circulation to exclude arterio-venous fistulas as a cause of the shunt seen on TTE. The investigators will also show the comparison in functional closure between classic and alternative device occluders.

NCT ID: NCT05462301 Recruiting - Echocardiography Clinical Trials

Normal Reference Range for Neonatal Echocardiography

NORRNE
Start date: November 15, 2022
Phase:
Study type: Observational

Echocardiography is the main method of bedside examination of neonatal cardiac morphology, which can timely diagnose congenital heart disease and quantitatively assess its severity, but the diagnosis and evaluation process depends on the normal range of neonatal echocardiography.At present, there have been normal reference standards for echocardiography in children and adults at home and abroad, but there is no uniform standard for echocardiographic parameters in newborns, especially premature infants.This study intends to carry out a national multicenter, prospective, observational study to establish the reference range of echocardiography at different time periods after birth in newborns, and stratified according to gestational age, birth weight and gender, to conduct a more accurate hemodynamic assessment of clinically critically ill newborns and guide the treatment of critically ill newborns in real time.

NCT ID: NCT05435573 Recruiting - Echocardiography Clinical Trials

Cardiac Output in Preeclamptic

Coload
Start date: August 17, 2022
Phase: N/A
Study type: Interventional

There is high incidence of hypertensive disorders during pregnancy.The maternal cardiovascular system had significant changes during pregnancy. The colloid oncotic pressure is decreased during preeclampsia.

NCT ID: NCT05340244 Completed - Echocardiography Clinical Trials

GE CVUS Device Evaluation

Start date: June 1, 2022
Phase: N/A
Study type: Interventional

The purpose of the study is to collect user feedback on the Vivid E95 ultrasound system and probes during clinical procedures on the device's intended population in order to optimize the device.

NCT ID: NCT05321849 Completed - Echocardiography Clinical Trials

Echocardiography-guided Percutaneous Patent Ductus Arteriosus Closure

Start date: March 12, 2019
Phase:
Study type: Observational [Patient Registry]

Since the first successful percutaneous closure under transoesophageal echocardiographic (TEE) guidance, many centres explored transcatheter procedures without fluoroscopy. This single centre study aims to show the feasibility and safety of percutaneous patent ductus arteriosus (PDA) closure under echocardiography-only guidance during our one-year experience. Patients with PDA were recruited for percutaneous PDA closure guided by either fluoroscopy or echocardiography-only in National Cardiovascular Center Harapan Kita. Patients were evaluated clinically and radiologically using TTE at 6, 24 and 48 hours after the procedure. Primary endpoint was the procedural success. Secondary endpoints were the procedural time and the rate of adverse events. Echocardiography-guided PDA closure is non-inferior to fluoroscopy-guided PDA closure, with similar procedural times. However, this method is operator-dependent and requires an experienced team for it to be performed successfully.