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Echinococcosis, Hepatic clinical trials

View clinical trials related to Echinococcosis, Hepatic.

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NCT ID: NCT06316154 Recruiting - Clinical trials for Echinococcosis, Hepatic

Presentation of Protoscolexes and Acephalocysts in the Fibrous Capsule Area of the Liver With Echinococcosis

PAFCLE
Start date: October 22, 2023
Phase:
Study type: Observational

The objective of the study is to determine the presence of germinal elements of echinococcosis in the liver parenchyma next to and in the thickness of the fibrous capsule of hydatid cysts.

NCT ID: NCT05989516 Completed - Clinical trials for Hydatid Cyst, Hepatic

Surgical Treatment of Hydatid Liver Disease

Start date: February 1, 2021
Phase:
Study type: Observational

The goal of this observational study is to show that cyst extraction with pericyst reduction and omentopexy is a suitable treatment for liver hydatid disease caused by E.Granulossus with a low rate of complication and recurrence.

NCT ID: NCT05986383 Not yet recruiting - Clinical trials for Primary Liver Cancer

Multi-center Clinical Study on the Decision Tree of Precision Hepatectomy in China Precision Hepatectomy Decision Tree

Start date: August 2023
Phase:
Study type: Observational [Patient Registry]

Liver failure (PHLF) after hepatectomy is a relatively serious postoperative complication. Previous studies have shown that liver reserve function is related to PHLF. The "Chinese expert consensus decision tree for hepatectomy" implemented recommends different surgical methods according to the liver function of patients and the standardized residual functional liver volume ratio, so as to achieve accurate hepatectomy and prolong the survival of patients. In the retrospective study, it showed the safety and effectiveness of the decision tree under the condition of extended hepatectomy indications, but it lacked prospective research to evaluate. Therefore, this study intends to evaluate the safety and effectiveness of hepatectomy under the guidance of Chinese expert consensus decision tree through prospective research.

NCT ID: NCT05420155 Completed - Clinical trials for Echinococcosis, Hepatic

Surgical Treatment of Liver Hydatid Cyst (SURGHIDA)

SURGHIDA
Start date: January 1, 2006
Phase:
Study type: Observational

The aim was to analyses the incidence and the independent factors associated with Textbook Outcome following surgical treatment of liver hydatid cysts (LHC).

NCT ID: NCT05113550 Completed - Clinical trials for Cystic Echinococcosis

Surgical Treatment of Hepatic Hydatidosis in Elderly Patients

ELDHIDA
Start date: January 1, 2021
Phase:
Study type: Observational

Cystic echinococcosis is a clinically complex chronic parasitic disease and a major socioeconomic problem in endemic areas. The safety of liver resection in elderly patients is often debated among medical professionals. The investigators analyzed the postoperative morbidity and mortality rates of elderly patients who underwent surgery at our unit.

NCT ID: NCT05090020 Recruiting - Clinical trials for Echinococcosis, Hepatic

Hypernatremia in Hydatid Cyst Treatment

Start date: February 1, 2021
Phase:
Study type: Observational

Hypertonic saline (HS) is one of the most widely used scolocidal agents in the treatment of hydatid cysts. Hypernatremia is one of the complications associated with the use of HS. It can cause hypernatremia, acid-base disorder, impaired lung, renal, cardiac and neurological functions and even death. Therefore, caution should be exercised in the use of HS, and open technique should be preferred in surgery.

NCT ID: NCT04271176 Active, not recruiting - Jaundice Clinical Trials

Jaundice as Initial Presentation of Liver Hydatidosis (ICTEHIDA)

ICTEHIDA
Start date: January 1, 2009
Phase:
Study type: Observational

The aim of this study is to evaluate patients with hepatic hydatidosis whose symptom at diagnosis was obstructive jaundice. As well as analyzing, the rate of performing preoperative ERCP, the results after surgery and morbidity

NCT ID: NCT02509884 Completed - Clinical trials for Alveolar Echinococcosis

Long-term Results of Comprehensive AE Management

Start date: January 1992
Phase: N/A
Study type: Observational

Comprehensive diagnosis and treatment of Alveolar Echinococcosis : A single-center, long-term observational study of 312 Patients in Germany. Human alveolar echinococcosis (AE) is the most Iethal human helminthic infection and is one of the 17 neglected tropical diseases prioritized by the World Health Organization (WHO). Its incidence is low in endemic regions of Central and Western Europe (0.03-0.05/100,000), but morbidity and treatment costs are high. In this observational study, the investigators assessed the severity of the disease using the PNM staging system and report on the long-term results of specific AE therapy in an interdisciplinary team of clinicians.

NCT ID: NCT01785212 Completed - Liver Neoplasms Clinical Trials

The Influence of Two Different Hepatectomy Methods on Transection Speed and Chemokine Release From the Liver

Start date: March 2013
Phase: N/A
Study type: Interventional

The CUSA (cavitron ultrasound surgical aspirator) is the method of choice for hepatic resection in our center. Recently a stapler-hepatectomy methods has been developed and approved for liver surgery using Covidien Endo-Gia stapler. The potential benefit of this method is a potential shorter transection time compared to the CUSA technique. Thus the investigators will perform a randomized controlled trial including 20 patients in the stapler-group and 20 patients in the CUSA control group. Primary endpoint will be transection speed. Secondary endpoints will be peri-operative (d-1, d0, d1, d3) cytokines concentration, T cell subsets, blood loss, morbidity, and a cost analysis.

NCT ID: NCT01643018 Completed - Clinical trials for Echinococcosis, Hepatic

Laparoscopic Versus Open Surgery for the Management of Cystic Echinococcosis of the Liver

Start date: November 2006
Phase: N/A
Study type: Interventional

Echinococcosis in humans is a parasitic tapeworm infection, caused by a larval stage (the metacestode) of Echinococcus species. The infection can be asymptomatic or severe, causing extensive organ damage and even death of the patient. Echinococcosis is one of the most neglected parasitic diseases and the lack of the prospective randomised studies supports this idea. Development of new drugs and other treatment modalities receives very little attention, if any. In most developed countries, Cystic Echinococcosis (CE) is an imported disease of very low incidence and prevalence and is found almost exclusively in migrants from endemic regions. In endemic regions, predominantly settings with limited resources, patient numbers are high. The aim of the hydatid cyst treatment is the death of the parasite and consequently the cure of the disease. It has to be done with a minimal risk and maximum comfort for the patient, and always paying attention to avoid complications, secondary hydatidosis, and relapses. There are several treatment modalities. Of them the most preferred surgical method is traditional cyst management through a laparotomy incision. Same can be done with laparoscopy. In the past 15 years significant advances in laparoscopic surgical skills and techniques combined with explosive advances in laparoscopic technology have encouraged the application of laparoscopy to the evaluation and treatment of solid organs including the liver. There are many studies about the laparoscopic treatment of liver hydatid cyst published in the literature and the feasibility of this procedure has been demonstrated by them. While the majority of them are case reports or case series, there are some relatively large series comparing open versus laparoscopic surgery published in the last decade, which all are not randomized trial.