View clinical trials related to Eating Disorders.
Filter by:This study will evaluate the effectiveness of fluoxetine versus placebo in reducing the rate of relapse of anorexia nervosa (AN) and enhancing the psychosocial and behavioral recovery of people who have been treated for AN.
Decreased bone strength is a serious medical problem present in many women with Anorexia Nervosa, or disordered eating. Women with weaker bones are more likely to suffer broken bones than women with normal bone strength. We are investigating whether a hormone that is naturally produced by the human body, called growth hormone, can help strengthen the bones of women with this type of disordered eating.
This research study is to evaluate the effectiveness, tolerability, and safety of lamotrigine therapy in the treatment of binge eating disorder associated with obesity. Lamotrigine has been approved by the Food and Drug Administration for the treatment of bipolar disorder, but has not been approved for use in the treatment of binge eating disorder with obesity.
This study will evaluate the effectiveness of a new approach to a normalization of eating program, based on principles of cognitive-behavioral therapy, in treating women with anorexia nervosa or bulimia nervosa.
The specific aim of this study is to examine the efficacy and safety of zonisamide compared with placebo in outpatients with binge eating disorder associated with obesity.
The purpose of this study is to evaluate the safety and effectiveness of topiramate compared to placebo in reducing the number of binge days in patients with moderate to severe binge-eating disorder associated with obesity.
This is a study to determine if the approach taken to treat patients in the Chrysalis Day Hospital Program will favourably effect their health status as assessed by Body Mass Index (BMI)
This study will compare specific family therapy, standard family systems therapy, and standard individual psychotherapy to determine which is most effective in treating adolescent anorexia nervosa.
This is the first-year part of a two-phase prospective study. The aims of the study are to investigate the prevalence rate of eating disorders in Taiwan, it's correlated psychosocial risk factors and establish the validity index of BITE. The study subjects consist of Taiwanese gifted dance high school students and age, sex, school-matched ordinary class students. All students completed questionnaires(Eating Altitude Test(EAT-26), Bulimic Investigatory Test, Ediburgh (BITE), Body Shape Questionnaire (BSQ), Physical Appearance Related Teasing Scale, Pubertal Develoment Scale, and Brief Symptom Rating Scale (BSRS) at first phase. All subjects who are above threshold (EAT-26 score≧20 and BMI≦17.5m2; the symptom scale score of BITE≧15 and/or severity scale≧5),and 10% of the sub-threshold cases need to receive second-phase interview by two senior psychiatrists. The contents of interview included SCID-IP, and risk factors assessment for eating disorders. The known risk factors included both personal factors (history of obesity, psychiatric, menstruation, teasing, or sexual or physical abuse, etc.) as well as family factors (parental problems, history of obesity, dieting, psychiatric illness etc.). Statistical analyses were conducted using SPSS 10.0 for Windows/PC. Categorical data were analyzed by nonparametric test (Chi-square test). ANOVA or Student’s t-test was used for continuous data analyses. Reliability is assessed by internal consistency and test-retest reliability. Inter-rater reliability was assessed by Kappa statistics. The sensitivity and specificity for eating disorders were calculated for individual screening instrument.ROC analyses were undertaken to evaluate the overall performance of the BITE +/- EAT in detecting eating disorder cases. Regression analysis was applied to determine predictors of disordered eating or eating disorder status. A value of P< 0.05 was considered statistically significant.
This is the second-year part of a two-phase prospective epidemiological study as well as a community case-controled study. The aims of the second year study are firstly, to investigate the clinical course and 1-year outcome of eating disorders in the community, as well as the prospective risk factors of eating disorders; secondly, a case-control design involving with other psychiatric disorders from the same study population is used for risk factors study. The study subjects are gifted dance high school students who participated the first-year study and are willing to participate the 2nd-year study (N=675). Screening questionnaires for eating disorders and general psychiatric disorders are EAT, BITE and CHQ-12. Other self-report questionnaires include perfectionism subscale of Eating Disorder Inventor-I (EDI), Rosenberg Self-esteem Scale (RSE), Eyseck Personality Scale, Pubertal Develoment Scale, and body figure test. Subjects who received interviews at the first-year study and those whose scores are above the threshold of the screening questionnaires need to receive interviews at 2nd phase. The criteria of interview threshold included EAT≧20+ BMI<18.5Kg/m2, symptom scale of BITE ≧15 and/or severity scale of BITE≧5, and CHQ ≧4. The content of interview included structured diagnostic interview (SCID-IP 1995) as well as risk factors assessment. Each time a subject with bulimia nervosa was recruited, one matched control subject with no mental illness general psychiatric diagnosis was sought from the same class or school. Potential psychiatric control subjects were identified from their scores on the CHQ. The psychiatric control subjects were required to have no current or past eating disorders. The contents of risk factor assessments include personal vulnerability and family problems. The relationships between individual risk factors and case status were assessed by univariate analysis. Conditional logistic analysis was used for multivariate analysis of risk factors prediction for eating disorders. To assess the relative importance of different types of exposure, the relationship between case status and exposure in each domain were first assessed by univariate analysis and then in multivariate stepwise regression analyses.