Early-Stage Breast Cancer Clinical Trial
Official title:
A Phase 3 Trial of Accelerated Whole Breast Irradiation With Hypofractionation Plus Sequential Boost for Early Stage Breast Cancer
A Phase III trial of accelerated whole breast irradiation with hypofractionation plus concurrent boost versus standard whole breast irradiation plus sequential boost for early-stage breast cancer.
Prospective randomized trials have established the principle that hypofractionation may be used for whole breast radiation with acceptable toxicity and equal local control as conventional 50 Gy/ 2 Gy fractionation. However, numerous questions remain to be answered before hypofractionation is accepted for use widely in the United States. ;
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