Tangential Radiation Therapy Without Axillary Dissection in Breast Cancer

Early-Stage Breast Cancer Clinical Trial

Official title: Tangential Radiation Therapy Without Axillary Dissection in Early-Stage Breast Cancer

Status Completed

Clinical Trial Summary

The purpose of this study is to evaluate whether treatment to the axilla (area under the arm) can be safely minimized by omitting axillary surgery and full axillary radiation therapy and replacing it with radiation therapy to the breast and lower axilla.

Clinical Trial Description

• Patients will have undergone conservative breast surgery without axillary dissection prior to enrollment in this study.

• Patients will receive radiation therapy to the breast, including the lowest axillary lymph nodes, over a period of 6 1/2 weeks.

• No radiation will be specifically directed toward the upper axilla or supraclavicular lymph nodes.

• Patients will also receive 5 years of tamoxifen or another type of hormone therapy determined by the medical oncologist.

• Follow-up visits will occur every 6 months and mammograms every 12 months. ;

Related Conditions & MeSH terms

• Breast Neoplasms
• Early-Stage Breast Cancer

• NCT number: NCT00165243
• Study type: Interventional
• Source: Dana-Farber Cancer Institute
• Status: Completed
• Phase: Phase 2
• Start date: September 1998
• Completion date: December 2016