Clinical and Molecular Aspects of Early Osteoarthritis

Early Osteoarthritis Clinical Trial

Official title: Clinical and Molecular Aspects of Early Osteoarthritis

Status Completed

Clinical Trial Summary

The etiology of osteoarthritis is varied, ranging from multifactorial, environmental to monogenic. In individuals in whom osteoarthritis appears earlier than in the general population, it is called early osteoarthritis. To our knowledge, there are no large-scale genetic studies on people with early osteoarthritis. The investigators therefore sought to study the causes of monogenic osteoarthritis in people suffering from early non-syndromic osteoarthritis.

Material and method From 2013 to 2019, experts in constitutional bone disease sent patients with non-syndromic early osteoarthritis for genetic analysis to our center of competence for constitutional bone diseases. The sequencing of a panel of genes was carried out by NGS.

Clinical Trial Description

n/a

Related Conditions & MeSH terms

• Early Osteoarthritis
• Osteoarthritis

• NCT number: NCT04267510
• Study type: Observational
• Source: University Hospital, Montpellier
• Status: Completed
• Start date: January 1, 2013
• Completion date: January 1, 2020