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Early Childhood Caries clinical trials

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NCT ID: NCT04958005 Completed - Clinical trials for Early Childhood Caries

Salivary Interleukin-32, Interleukin-10, Interleukin-6 and Tumor Necrosis Factor-alpha Levels in Children

Start date: July 1, 2021
Phase:
Study type: Observational

This study aimed to evaluate the levels of interleukin 10, interleukin 6, interleukin 32 and tumor necrosis factor-alpha (TNF-α) in saliva of children with early childhood caries.

NCT ID: NCT04923581 Recruiting - Clinical trials for Dental Caries in Children

Effect of Optimized Behavioural Intervention Using The Multi-Phase Optimization Strategy (MOST).

Start date: July 8, 2023
Phase: N/A
Study type: Interventional

In the current study, MOST approach is proposed, to engineer an oral health behavior modification intervention, to increase the engagement of mothers in brushing their pre-school children's teeth.

NCT ID: NCT04765904 Not yet recruiting - Clinical trials for Early Childhood Caries

Clinical Efficiency and Treatment Failure of Hall Versus SDF Techniques in the Management of Carious Primary Molar.

Start date: August 1, 2021
Phase: N/A
Study type: Interventional

This study will compare two non- invasive treatment options: Hall technique and 38% Silver diamine fluoride. Both are methods used to create a more favorable environment without removal of caries leading to the arrest of the progression of demineralization process and restoring the function of the diseased molars.

NCT ID: NCT04758221 Completed - Dental Caries Clinical Trials

Clinical Performance of Composite Coronal Build -Up in Mutilated Primary Incisors: 3 Years Results

Start date: June 2016
Phase: N/A
Study type: Interventional

Prospective single arm study was to evaluate the clinical success and/ or failure of resin-bonded composite coronal build-up retained by macro-retentive grooves for restoring mutilated primary maxillary incisors after 36 months. Design: Forty two primary incisors out of 14 children, aged 2-5years, treated in a private pediatric dental practice under general anesthesia and presented for follow-up after 6, 12, 18, 24 and 36 months included in the study. The parameters recorded at the baseline and at the follow-up intervals were: retention, colour match, the number and location of the decayed surfaces (recurrent caries), chipping /fracture of the restoration and loss of restoration (failure). Materials and Methods: A total of (14) pediatric patients aged from 2-5 years presented with mutilated primary anterior teeth due to caries or trauma and treated comprehensively under general anesthesia from June 2016 to June 2017 were enrolled in this study. A total of (42) decayed or traumatized primary anterior teeth were treated with composite coronal build-up based on the micro-mechanical adhesive procedure of composite resin in addition to macro mechanical retentive grooves created on the lateral sides of the cervical one third of the roots of treated teeth. The patients returned at the end of 6, 12, 18, 24 and 36 months and received clinical examinations. Another dentist (co-author) who did not attend the treatment evaluated the strip crowns clinically by modified United States Public Health Service (USPHS) criteria.

NCT ID: NCT04737057 Not yet recruiting - Clinical trials for Early Childhood Caries

Clinical Efficiency and Child's Behavior of Hall Versus SDF Techniques in the Management of Carious Primary Molar:

Start date: May 1, 2021
Phase: N/A
Study type: Interventional

This study will compare two non- invasive treatment options: Hall technique and 38% Silver diamine fluoride. Both are methods used to create a more favorable environment without removal of caries leading to the arrest of the progression of demineralization process and restoring the function of the diseased molars.

NCT ID: NCT04665219 Recruiting - Health Behavior Clinical Trials

HBM for Empowering Parental Toothbrushing and Sugar Intake Control

Start date: September 1, 2020
Phase: N/A
Study type: Interventional

It has been recognized that oral health education for parents is critical for the prevention of early childhood caries (ECC). Few parents practiced caries prevention procedures for their children in daily life, though. Inspired by Health Belief Model (HBM) and using text messaging as a vehicle, a novel intervention scheme will be developed in this study. The objective of the present randomized clinical trial (RCT) is to investigate the effectiveness of the HBM-based behavioral intervention using text message to reduce early childhood caries of children at age 4 through promoting the parental oral health care behaviors (toothbrushing and sugar intake control) for their young children compared to conventional oral health education. This RCT will recruit child-parent dyads in 26-36 child help centers or kindergartens with nursery classes located in Hong Kong. A total of 518-628 dyads will be recruited and randomly allocated into the test or control group with a 1:1 ratio. For parents in the test group, the intervention will consist of a set of HBM-based text messages sent regularly in the following 48 weeks. A standard text message will be sent to the parents in the control group. The primary outcome will be dental caries measured by dmft/dmfs of the children at 4 years old. By HBM-based intervention via a low-cost text messaging vehicle, it should be able to help the parents establish proper oral health behaviors for their children and safeguard the oral health of children in Hong Kong.

NCT ID: NCT04655430 Completed - Clinical trials for Early Childhood Caries

Effect of Application Time of 38% Silver Diamine Fluoride Solution on Arresting Dental Caries in Preschool Childre

Start date: October 1, 2021
Phase: Phase 2/Phase 3
Study type: Interventional

To determine the optimal application time of silver diamine fluoride (38% SDF) in arresting dental caries in the primary teeth of preschool children.

NCT ID: NCT04556175 Terminated - Dental Caries Clinical Trials

Great Beginnings for Healthy Native Smiles: An Early Childhood Caries Prevention Project

Start date: March 29, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether a bundled best practices oral health intervention utilizing motivational interviewing versus a didactic maternal and child healthy lifestyle intervention will reduce childrens' decayed, missing and/or filled primary tooth surfaces (dmfs) measured over a 2-3 year period.

NCT ID: NCT04514094 Completed - Clinical trials for Early Childhood Caries

Silver Diamine Fluoride Effectiveness Versus Atraumatic Restorative Treatment in Arresting ECC

Start date: January 1, 2018
Phase: N/A
Study type: Interventional

The study was conducted to evaluate the effectiveness of the biannual application of 38% silver diamine fluoride in arresting early childhood caries when compared to atraumatic restorative treatment.

NCT ID: NCT04456335 Completed - Clinical trials for Early Childhood Caries

Investigation of Supragingival Plaque Microbiome in Early Childhood Caries

Start date: March 4, 2019
Phase:
Study type: Observational

The purpose of this study was to characterize the supragingival plaque microbiome in children with early childhood caries and identify potential microorganisms associated with caries.