Early Breast Cancer Clinical Trial
Official title:
A Multicenter, Open-label, Single-arm, Phase II Clinical Trial of Nab-paclitaxel in Combination With Pyrotinib in Adjuvant Therapy for Lymph Node-negative and Small Tumor HER2-positive Breast Cancer
This is a multicenter, open-label, single-arm, prospective, phase II study. conducted to evaluate the efficacy, safety and tolerability of nab-paclitaxel plus pyrotinib in patients with lymph node-negative and tumor size ≤3 cm, HER2 positive breast cancer.
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| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Withdrawn |
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GM1 in the Treatment of Neurotoxicity Induced by Albumin-bound Paclitaxel
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Phase 2 | |
| Completed |
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A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Giredestrant Plus Palbociclib Compared With Anastrozole Plus Palbociclib for Postmenopausal Women With Estrogen Receptor-Positive and HER2-Negative Untreated Early Breast Cancer (coopERA Breast Cancer)
|
Phase 2 | |
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Phase 3 | |
| Terminated |
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N/A | |
| Recruiting |
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Cardiac Safety and Efficacy for Early-stage Breast Cancer Patients Treated With Pegylated Liposomal Doxorubicin（PLD)
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Phase 3 | |
| Active, not recruiting |
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Prospective Observational Study of Adjuvant Hormone Treatment in Estrogen-receptor Positive Premenopausal Early Breast Cancer Patients
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||
| Terminated |
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A Pharmacodynamics Pre-surgical Study of LEE011 in Early Breast Cancer Patients (MONALEESA-1)
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Phase 2 | |
| Active, not recruiting |
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Neoadjuvant Study Chemotherapy vs Letrozole + Abemaciclib in HR+/HER2- High/Intermediate Risk Breast Cancer Patients
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Phase 2 | |
| Completed |
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Evaluation of Brain Function Before and After Standard Chemotherapy for Early Breast Cancer
|
N/A | |
| Recruiting |
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Efficacy and Safety of Dalpiciclib With Endocrine Therapy as Adjuvant Treatment in HR+/ HER2- Early Breast Cancer
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Phase 2 | |
| Recruiting |
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Radiotherapy in Preoperative Setting With CyberKnife for Breast Cancer
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N/A | |
| Completed |
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Activity Program During Aromatase Inhibitor Therapy
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N/A | |
| Completed |
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Feasibility of Ambulatory Surgery for Early Breast Cancer
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N/A | |
| Completed |
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|
Phase 1 | |
| Recruiting |
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A Comparison of Intra-operative Radiotherapy Boost With External Beam Radiotherapy Boost in Early Breast Cancer.
|
N/A | |
| Completed |
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Arthralgia During Anastrozole Therapy for Breast Cancer
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Phase 4 | |
| Completed |
NCT03493854 -
A Study to Evaluate the Pharmacokinetics, Efficacy, and Safety of Subcutaneous Administration of the Fixed-Dose Combination of Pertuzumab and Trastuzumab in Combination With Chemotherapy in Participants With HER2-Positive Early Breast Cancer
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Phase 3 | |
| Recruiting |
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The DBCG Proton Trial: Photon Versus Proton Radiation Therapy for Early Breast Cancer
|
N/A | |
| Active, not recruiting |
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A Study to Evaluate Patient Preference for Home Administration of Fixed-Dose Combination of Pertuzumab and Trastuzumab for Subcutaneous Administration in Participants With Early or Locally Advanced/Inflammatory HER2-Positive Breast Cancer
|
Phase 3 | |
| Not yet recruiting |
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Trial for Treatment of High Risk BC With Two Sequences of Neoadjuvant Chemotherapy With Pembrolizumab
|
Phase 2 |