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A Pharmacodynamics Pre-surgical Study of LEE011 in Early Breast Cancer Patients (MONALEESA-1) — MONALEESA-1  

Early Breast Cancer Clinical Trial

Official title:
A Randomized Pre-surgical Pharmacodynamics Study to Assess the Biological Activity of LEE011 Plus Letrozole Versus Single Agent Letrozole in Primary Breast Cancer

Clinical Trial Summary

This is a multi-center, open-label Phase II randomized pre-surgical pharmacodynamics study.

Clinical Trial Description

This randomized pre-surgical pharmacodynamics study will assess the biological activity of LEE011 plus letrozole versus single agent letrozole in primary breast cancer. ;

Study Design

Allocation: Randomized, Endpoint Classification: Pharmacodynamics Study, Intervention Model: Parallel Assignment, Masking: Open Label

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01919229
Study type Interventional
Source Novartis
Contact
Status Terminated
Phase Phase 2
Start date October 2013
Completion date September 2014
View Details
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