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Early Breast Cancer clinical trials

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NCT ID: NCT06435104 Not yet recruiting - Early Breast Cancer Clinical Trials

Aromatherapy in the Treatment of Early Breast Cancer

Start date: May 2024
Phase: Phase 2
Study type: Interventional

Breast cancer is a major threat to women's health, and chemotherapy is one of the most important treatment method. Chemotherapy is cytotoxic , and has a positive tumor immune effect. However, it is worth noting that anxiety caused by breast cancer itself and adverse reactions of chemotherapy not only affects the patients' quality of life, but also reduces the treatment compliance and even survival benefits of patients. Previous literatures have shown that aromatherapy may improve chemotherapy-induced anxiety and even affect anti-tumor immunity. Therefore,we envisage that aromatherapy conbimed with chemotherapy in the treatment of breast cancer in clinical practice has the advantages of improving efficacy and survival. However, there is still a lack of relevant clinical studies. We planned to design a prospective clinical trial to evaluate the efficacy and safety of aromatherapy combined with chemotherapy on anxiety, relevant sympathetic neurotransmitters and tumor immunity in breast cancer patients.

NCT ID: NCT06404736 Not yet recruiting - Neoadjuvant Therapy Clinical Trials

QL1706 Plus Chemotherapy as Neoadjuvant Therapy in Early High-Risk TNBC Breast Cancer

QUEEN-Dream
Start date: May 7, 2024
Phase: Phase 2
Study type: Interventional

This study will look at the efficacy and safety of QL1706 plus albumin-bound paclitaxel and carboplatin in a neoadjuvant setting, in high-risk, TNBC early breast cancer.

NCT ID: NCT06404463 Not yet recruiting - Neoadjuvant Therapy Clinical Trials

QL1706 Plus Chemotherapy as Neoadjuvant Therapy in Early High-Risk ER+/HER2- Breast Cancer

QUEEN-Neo
Start date: May 6, 2024
Phase: Phase 2
Study type: Interventional

This study will look at the efficacy and safety of QL1706 plus albumin-bound paclitaxel followed by AC/EC in a neoadjuvant setting, in high-risk, ER+/HER2- early breast cancer.

NCT ID: NCT06371807 Not yet recruiting - Clinical trials for Triple Negative Breast Cancer

Trial for Treatment of High Risk BC With Two Sequences of Neoadjuvant Chemotherapy With Pembrolizumab

KEYPARTNER
Start date: July 2024
Phase: Phase 2
Study type: Interventional

Phase II, randomized, Active-controlled open label trial for treatment of high risk, HR-/HER2- (triple negative) breast cancer, with two sequences of neoadjuvant chemotherapy on a background of pembrolizumab

NCT ID: NCT04659499 Not yet recruiting - Early Breast Cancer Clinical Trials

Nab-paclitaxel in Combination With Pyrotinib in Postoperative Adjuvant Therapy for HER2-positive Breast Cancer

Start date: January 2021
Phase: Phase 2
Study type: Interventional

This is a multicenter, open-label, single-arm, prospective, phase II study. conducted to evaluate the efficacy, safety and tolerability of nab-paclitaxel plus pyrotinib in patients with lymph node-negative and tumor size ≤3 cm, HER2 positive breast cancer.