An Online Intervention to Reduce E-cigarette Use and Susceptibility to Smoking in Young Adults

E-cigarette Use Clinical Trial

Official title:

Development of An Online, Theory-Based Intervention to Reduce E-cigarette Use and Susceptibility to Smoking in Young Adults: A Pilot Study

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT06129123
• Other study ID #: UP-23-00005-AM001
• Status: Not yet recruiting
• Phase: N/A
• Start date: March 1, 2026
• Est. completion date: March 1, 2027

Study information

• Verified date: November 2023
• Source: University of Southern California
• Contact: Shirin Contracts and Grants Coordinator
• Phone: 310-918-0538
• Email: shirin.mistry[@]med.usc.edu
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The goal of this intervention development and pilot clinical trial is to determine whether receiving the brief online intervention results in greater reductions in past 7-day e-cigarette use frequency and smoking susceptibility over an 8-week period compared to receiving the control condition in young adults who currently use e-cigarettes. Participants in the experimental condition will be asked to complete the 30-minute mobile-based program. Participants in the assessment-only control will be given the option to access the intervention after they complete their final survey at 8 weeks. All participants will complete our online surveys at baseline as well as 2-weeks, 4-weeks, and 8-weeks post-randomization. Researchers will compare outcomes among the intervention and control groups to determine the efficacy of the intervention.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 100
• Est. completion date: March 1, 2027
• Est. primary completion date: March 1, 2027
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 24 Years

Eligibility

Inclusion Criteria:

• be between the ages of 18 to 24
• be able to read English
• report vaping at least one day per week in the past month
• report no history of cigarette use at screening and baseline.

Exclusion Criteria:

• reporting mental health, other drug, or alcohol use problems
• currently receiving nicotine cessation services

Related Conditions & MeSH terms

• Disease Susceptibility
• E-cigarette Use

Intervention

Behavioral:
• Live Free From E-cigarettes
This is a 30-minute online educational program that focuses on providing information about e-cigarette and smoking social norms, harms of e-cigarettes and cigarettes, and ways to quit or reduce using e-cigarettes.

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
University of Southern California

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	E-cigarette Use	Participants will report the number of (1) days they vaped, (2) times they picked up their device to vape per day, and (3) puffs they took before putting their vaping device away per day in the past 7 days and 30 days	8 weeks
Primary	Smoking Susceptibility	4-item Expanded Susceptibility to Smoking Index (ESSI)	8 weeks
Secondary	Perceived harms and benefits of vaping	Using the 21-item Short Form Vaping Consequences Questionnaire (S-VSQ), participants will rate the likelihood that each consequence will occur when they vape.	8 weeks
Secondary	Perceived harms and benefits of smoking	Using the 21-item Short Form Smoking Consequences Questionnaire (S-SCQ), participants will rate the likelihood that each consequence will occur when they smoke.	8 weeks
Secondary	Motivation to vape	Participants will select which option best describes their interest in e-cigarette use: plan to stop (coded as 1), decrease (2), continue (3) or increase (4) vaping.	8 weeks
Secondary	Motivation to smoke	Participants will report if they plan to start smoking (yes/no).	8 weeks
Secondary	Quitting vaping self-efficacy	Participants rate their confidence about quitting vaping "someday" and "in the next 6 months" on a 5-point scale.	8 weeks