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Evaluating E-Cigarette Nicotine Form, Concentration, and Flavors Among Youth

E-cigarette Use Clinical Trial

Official title:
Evaluating E-Cigarette Nicotine Form, Concentration, and Flavors Among Youth

Clinical Trial Summary

This clinical trial examines the influence of nicotine form, concentration, and e-liquid flavor on youth vaping behavior, as well as the heart and lung effects associated with this behavior. Electronic cigarette (e-cig) "vaping", while being promoted as a safer alternative to conventional cigarettes, has disproportionately attracted adolescents and young adults ("youth"). This trial may help researchers understand how nicotine form, concentration, and flavor affects people's vaping behaviors and health.

Clinical Trial Description

We will examine the influence of nicotine form and concentration, and e-liquid flavor on youth vaping behavior, nicotine uptake, abuse liability, toxicant exposure, and acute cardiovascular and pulmonary effects. Participants will complete 9 vaping sessions. Each vaping session will include a standardized, 5-minute, 10-puff vaping bout (30 seconds between each puff) followed by 30 minutes of ad libitum (as desired) vaping. During the first session, participants will use their own e-cig and e-liquid; for the following 8 sessions, participants will vape a study-provided e-cig and e-liquid. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05458895
Study type Interventional
Source Ohio State University Comprehensive Cancer Center
Contact Toral R Mehta, PhD
Phone 614-753-0021
Email Toral.Mehta@osumc.edu
Status Recruiting
Phase N/A
Start date December 2, 2021
Completion date December 31, 2024
View Details
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