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Clinical Trial Summary

Prospective cohort study to evaluate the utility of quantitative CT analysis to assess ventilation and perfusion defects in patients with Post-acute Sequelae of SARS-CoV-2 (PASC) and functional limitations

Clinical Trial Description

This is a study to describe the overall pattern of lung ventilation and perfusion defects in individuals with PASC. Subjects with PASC with a documented history of COVID-19 and persistent symptoms of fatigue, dyspnea, and/or exercise intolerance will complete questionnaires, and undergo pulmonary function tests, 6-minute walk tests, and a low dose CT chest to describe the overall pattern of lung regional ventilation and blood distribution and to compare this pattern to asymptomatic controls with and without prior COVID-19. ;

Study Design

Related Conditions & MeSH terms

NCT number NCT05866952
Study type Observational
Source Tufts Medical Center
Contact Bipin Malla
Phone 617-636-6304
Status Recruiting
Start date May 12, 2023
Completion date May 31, 2024

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