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Dysphagia clinical trials

View clinical trials related to Dysphagia.

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NCT ID: NCT01738997 Completed - Dysphagia Clinical Trials

Endoscopical Dilation of Benign Esophageal Strictures

Start date: December 2003
Phase: N/A
Study type: Interventional

Although balloon dilatation is the primary treatment for benign dysphagia, information about the optimal inflation time is lacking. The aim of the current pilot study was to compare 10 seconds inflation time, with 2 minutes inflation time, regarding the efficacy

NCT ID: NCT01723358 Completed - Dysphagia Clinical Trials

Neuromuscular Electrical Stimulation (NMES) Treatment Technique Therapy in the Management of Young Infants With Severe Dysphagia

Start date: September 2010
Phase: Phase 2
Study type: Interventional

The goal of this study is to obtain data that well help inform the feasibility and design of a randomized control trial of the therapeutic Neuromuscular Electrical Stimulation (NMES) technique in improving the swallowing function of young infants presenting with severe dysphagia.

NCT ID: NCT01702701 Withdrawn - Dysphagia Clinical Trials

Eosinophilic Esophagitis Treatment: Montelukast vs Fluticasone

Start date: January 2012
Phase: Phase 3
Study type: Interventional

This study will compare response to treatment of Eosinophilic Esophagitis with montelukast vs standard therapy fluticasone. Investigators hypothesize that montelukast is equally effective in treating symptoms and histology of EoE when compared to fluticasone. The study will be conducted at multiple sites with Medical College of Wisconsin as the coordinating site. After identification and recruitment all patients will be randomized (provider blinded) to one of two medications: montelukast 10mg po qday vs fluticasone 440mcg po bid. Patients will also complete a pretreatment, 6 week therapy and 12 week therapy questionaire. They will then undergo a repeat endoscopy to evaluate endoscopic and histologic response.

NCT ID: NCT01697891 Enrolling by invitation - Clinical trials for Head and Neck Cancer

A Pilot Study of ALTENS in Improving Dysphagia Induced by IMRT for Head and Neck Cancers

Start date: October 2012
Phase: Phase 1/Phase 2
Study type: Interventional

Study hypothesis: ALTENS techniques, administered within the first 3 months after radiation completion, can improve radiation-induced dysphagia and associated symptoms in head and neck cancer patients. This beneficial effect is mediated by the reduction of chronic inflammatory response of swallowing musculature to radiation, consequently a reduction in muscle fibrosis. Primary study objective: To evaluate the effectiveness of ALTENS in relieving radiation-induced dysphagia. Eating Assessment Tool (EAT-10) scores will be used for this primary study endpoint.

NCT ID: NCT01651975 Completed - Dysphagia Clinical Trials

Evaluation of Two Different Thickening Products in Patients With Dysphagia

Start date: November 2009
Phase: Phase 4
Study type: Interventional

Dysphagia is extremely common. The importance of providing adequate nutritional support to persons with dysphagia is the cornerstone to exceptional care. Diet modification with thickening agents is an essential aspect of this nutritional support. The purpose of this investigation is to compare the efficacy of a starch based (Thickenup or TU) to a gel based thickening agent (Thickenup Advance or TUA).

NCT ID: NCT01570023 Completed - Dysphagia Clinical Trials

Study of Tongue Strengthening for Swallowing Problems

Start date: April 2012
Phase: N/A
Study type: Interventional

This study is a multisite, randomized clinical trial to determine the effectiveness of an 8-week rehabilitative exercise regime performed by patients with swallowing problems, termed dysphagia, compared to a control group of patients with swallowing problems who do not exercise, but receive standard clinical care. One hundred male and female patients will take part in this study from eight participating facilities around the country.

NCT ID: NCT01507207 Completed - Quality of Life Clinical Trials

Pediatric Dysphagia Outcomes After Injection Laryngoplasty for Type I Laryngeal Cleft

Start date: January 2012
Phase: Phase 4
Study type: Interventional

Type I laryngeal cleft evaluation and treatment in the pediatric population is an emerging science. The largest published series of pediatric patients with type I laryngeal clefts shows conflicting evidence in terms of outcomes, resolution of dysphagia and method of treatment. A comparison of quality of life outcomes before and after injection laryngoplasty has not been carried out. The investigators hypothesize that injection laryngoplasty significantly improves symptoms and quality of life related to dysphagia in a pediatric population with laryngeal clefts.

NCT ID: NCT01501071 Completed - Dysphagia Clinical Trials

Esophageal Calibration During Laparoscopic Fundoplication Reduces Dysphagia

Start date: January 2009
Phase: N/A
Study type: Interventional

Gastro esophageal reflux is the most common benign disease of the esophagus and Laparoscopic Nissen fundoplication became the standard surgical treatment of this disease. Although being almost transient postoperative dysphagia is still a common complaint following this procedure. The aim of this study is to investigate the effect of inserting a soft structured and blunt mounted 39 F orogastric tube to postoperative dysphagia.

NCT ID: NCT01496924 Recruiting - Dysphagia Clinical Trials

Swallowing Rehabilitation of Dysphagic Tracheostomized Patients Under Mechanical Ventilation at ICU

Start date: January 2008
Phase: Phase 2
Study type: Interventional

There is an association between increased risk of oropharyngeal dysphagia and artificial ventilation through endotracheal tube, followed by tracheostomy. The aim of the present study is to analyze the outcomes of an early swallowing rehabilitation program of dysphagic tracheostomized patients under mechanical ventilation at the intensive care unit.

NCT ID: NCT01479231 Withdrawn - Dysphagia Clinical Trials

Predictors of Proton Pump Inhibitor (PPI) Response in Eosinophilic Esophagitis

Start date: March 2012
Phase: Phase 1/Phase 2
Study type: Interventional

The investigators will determine the prevalence of gastroesophageal reflux disease (GERD) in Eosinophilic Esophagitis (EoE) and importantly determine the predictors of response to Proton Pump Inhibitor (PPI) therapy in EoE. Moreover, the investigators will determine the effect of GERD on the location of esophageal eosinophilia.