Dysphagia, Esophageal Clinical Trial
Official title:
Esophageal Impedance and Manometry Measurements and Dysphagia Symptom Scoring
Comparison of manometry measurements and EndoFlip Balloon measurements in patients with dysphagia and a known esophageal diagnosis
Gastrointestinal (GI) motility problems are very common in the general population. Dysphagia,
difficulty swallowing, is one of the most common issues in gastroenterology. In many
patients, esophageal obstruction is not identified despite workup with upper endoscopy or
barium swallow x-ray. Patients are often referred to the Motility Laboratory for evaluation
of non-obstructive dysphagia. Transnasal esophageal manometry-impedance is a diagnostic test
to measure the pressures and coordination of the esophagus during swallowing. The Endolumenal
Functional Lumen Imaging Probe (EndoFLIP) is another instrument used to measure the lumen
distensibility of the esophagus and pylorus. Both tests are FDA-approved and are currently
being used in clinical practice. However, correlation of the results obtained from these
tests with clinical syndromes and symptoms is not clearly understood. Furthermore, the
relationship between esophageal impedance-manometry and EndoFLIP results has never been
defined.
The primary Aim is to develop a registry of patients undergoing esophageal
manometry-impedance and Endoflip from the GI Motility Lab at the IU University Hospital
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