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Dysmenorrhea clinical trials

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NCT ID: NCT02214550 Completed - Chronic Pain Clinical Trials

Chronic Pain Risk Associated With Menstrual Period Pain

CRAMPP
Start date: July 2014
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine if some women with dysmenorrhea (painful periods) are at higher future risk of developing chronic pelvic pain (CPP) and if oral contraceptives (OC) can be used to reverse this chronic pain risk. Investigators will examine whether dysmenorrhea produces CPP via repetitive cross organ sensitization (COS) episodes. The use of cyclical OCs to eliminate dysmenorrhea is expected to reduce COS and decrease the risk of developing CPP.

NCT ID: NCT02205970 Completed - Clinical trials for Primary Dysmenorrhea

Application of Electrical Neurostimulation Transcutaneous in Patients With Primary Dysmenorrhea.

Start date: August 2010
Phase: N/A
Study type: Interventional

The present study aims to verify the analgesic potential of a new methodological proposal for application for transcutaneous electrical nerve stimulation (TENS interactive) using patients with primary dysmenorrhoea and compare it with placebo in a randomized double blind study with convenience sample.

NCT ID: NCT02183025 Completed - Dysmenorrhea Clinical Trials

Efficacy and Safety Study of Meloxicam Versus Mefenamic Acid in Patients With Dysmenorrhea

Start date: January 1998
Phase: Phase 2
Study type: Interventional

To access the efficacy and safety of Meloxicam 7.5 mg and 15 mg once daily compared with Mefenamic acid 500 mg t.i.d. over a treatment period of 3-5 days, during an observation period of 3 menstrual cycles, for the symptomatic relief of primary dysmenorrhea

NCT ID: NCT02114723 Completed - Clinical trials for Primary Dysmenorrhea

Effectiveness of Medical Taping Concept in Primary Dysmenorrhea

Start date: February 2014
Phase: N/A
Study type: Interventional

Determine the effectiveness of a proceeding under kinesio tape on pain and systemic symptoms most frequently described in primary dysmenorrhea.

NCT ID: NCT02026206 Completed - Clinical trials for Primary Dysmenorrhea

Low-level Light Therapy for Primary Dysmenorrhea

Start date: October 2011
Phase: Phase 3
Study type: Interventional

The purpose of this study was to evaluate the effectiveness of a self-therapeutic approach of skin adhesive low-level light therapy (LLLT) in females with primary dysmenorrhea (PD).

NCT ID: NCT01972906 Completed - Clinical trials for Primary Dysmenorrhea

Moxibustion for Primary Dysmenorrhea

Start date: February 2012
Phase: Phase 0
Study type: Interventional

Hypothesis: Moxibustion is effective for managing primary dysmenorrhea. Aim: To attest the effectiveness and safety of moxibustion for primary dysmenorrhea. Design: A randomized controlled trial. 152 participants will be included. Two arms: moxibustion treatment group and ibuprofen control group.

NCT ID: NCT01892904 Completed - Dysmenorrhea Clinical Trials

Comparative Study of BAY86-5300 With a Flexible Extended Regimen for Dysmenorrhea

Start date: July 2013
Phase: Phase 3
Study type: Interventional

The is a multi-center, randomized, open-label, active-controlled, parallel-group comparative study (24-week treatment period). The objective of this study is to prove the superiority of BAY 86-5300 with flexible extended regimen for treatment of dysmenorrhea to BAY 86-5300 with 28-day cyclic regimen in terms of primary efficacy variable, number of days with dysmenorrheic pain over 140 days of evaluation period. In addition, the long-term safety of the flexible extended regimen of BAY86-5300 in patients treated for one year will be investigated.

NCT ID: NCT01670656 Completed - Dysmenorrhea Clinical Trials

A Study to Evaluate the Effect of Contraceptive Vaginal Rings on Primary Dysmenorrhea (P08257/MK-8175A/MK-8342B-057)

Start date: January 21, 2013
Phase: Phase 2
Study type: Interventional

The study investigates four vaginal ring groups with respect to relief of primary dysmenorrhea, and should identify at least one vaginal ring that shows clinically relevant treatment efficacy in relief of primary dysmenorrhea.

NCT ID: NCT01626235 Completed - Dysmenorrhea Clinical Trials

AMPED Outcomes Registry of Post-ED Pain Management

AMPED
Start date: July 2012
Phase: N/A
Study type: Observational

Study aims to assess patient-recorded outcomes of pain control medications prescribed in the ER after visits for specific painful injuries/illnesses.

NCT ID: NCT01601366 Completed - Adenomyosis Clinical Trials

LNG-IUS for Treatment of Dysmenorrhea

LNGIUSAD
Start date: April 2012
Phase: Phase 2
Study type: Interventional

Adenomyosis is a disease entity diagnosed when endometrial glands and stroma deep in the myometrium are associated with surrounding myometrial hypertrophy. The finding classically associated with adenomyosis is excessive uterine bleeding accompanied by worsening dysmenorrhea. The advent of endovaginal US has substantially improved the ability to diagnose adenomyosis. Different US features of adenomyosis have been reported, including uterine enlargement not explainable by the presence of leiomyomas, asymmetric thickening of the anterior or posterior myometrial wall, lack of contour abnormality or mass effect, heterogeneous poorly circumscribed areas within the myometrium, anechoic lacunae or cysts of varying sizes, and increased echotexture of the myometrium. Transvaginal power Doppler application is useful in studying the vascular tree of adenomyosis and can aid clinicians in planning the most appropriate therapeutic strategy. The differential diagnosis using power Doppler sonography is based on vascular characteristics. Adenomyosis is characterized by a preserved vascular texture supply that results in dilated spiral arteries running perpendicular toward the myometrium into the endometrial surface. Leiomyomata exhibits a vascular tree that typically circumscribes the solid mass. 2D transvaginal power Doppler angiography should be used to improve diagnostic sensitivity and facilitate appropriate therapeutic intervention. The levonorgestrel-releasing intrauterine system (IUS), Mirena, has been approved in Europe for contraception since 1990. Because of the suppressive effect of levonorgestrel on the endometrium, Mirena has also been proven to be effective for the management of menorrhagia and dysmenorrhea, and as a progestin component in postmenopausal hormone therapy. It was introduced in Taiwan in 1995 as an alternative therapy for idiopathic menorrhagia. Many cases of menorrhagia are caused by adenomyosis, and Mirena was, therefore, introduced for the treatment of adenomyosis in Taiwan. The current study is designed to evaluate the best treatment modality for treatment of adenomyosis clinical by assessment of dysmenorrhea and or chronic pelvic pain by visual analogue scale and menstrual blood loss by menstrual diary, imaging by ultrasound and Doppler indices.