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Dyslexia clinical trials

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NCT ID: NCT02964884 Recruiting - Clinical trials for Neurofibromatosis Type 1

Interventions for Reading Disabilities in NF1

Start date: November 2016
Phase: Phase 2
Study type: Interventional

Neurofibromatosis Type 1 (NF1) is a common genetic disorder that is associated with a four times greater risk of learning disabilities, including reading disabilities, and a deficiency of neurofibromin - a protein important in a signaling pathway that regulates learning and memory. Our previous work (NS49096) demonstrated that school-age children with NF+RD can respond to standard phonologically-based reading tutoring originally developed to treat reading disability in the general population. Combining our work with that by other researchers suggesting that a medication (Lovastatin) may counteract the effects of the deficient neurofibromin, and possibly ameliorate learning disabilities in NF1, the investigator propose to examine the synergistic effects of medication plus reading tutoring.

NCT ID: NCT02791841 Recruiting - Clinical trials for Developmental Dyslexia

Comparison of Interventions for Developmental Dyslexia

Start date: January 2016
Phase: N/A
Study type: Interventional

The purpose of the present study is to compare the effectiveness of Rhythmic Reading Training (RRT), a computer-assisted intervention method that combines sublexical reading exercises with rhythm processing, and that of an intervention resulting from the combination of two yet validated treatments for DD, namely, Bakker's Visual Hemisphere-Specific Stimulation (VHSS) and the Action Video Game Training (AVG). Finally, the effectiveness of the administration of only AVG is intended to be compared to other treatments. All interventions are administered for 13 hours over 9 days to a group of Italian students with DD aged 8-12.

NCT ID: NCT02217696 Recruiting - Clinical trials for Developmental Dyslexia

Prediction and Intervention in Developmental Dyslexia

LEXI
Start date: July 2013
Phase: N/A
Study type: Interventional

The long-term goal of this study is to improve prediction of poor reading outcome at preschool age by using a combination of behavioural and neuroimaging measures and to evaluate a specific computerized training program to support children with problems during reading acquisition.

NCT ID: NCT02068261 Recruiting - Depression Clinical Trials

Working Memory Training in Adults With Substance Abuse and Executive Function Deficits.

Start date: January 2014
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the effects of a computerized working memory training program on substance abuse, psychosocial functioning, cognitive performance and psychiatric problems in adults with substance abuse and attention problems.

NCT ID: NCT00111371 Recruiting - Dyslexia Clinical Trials

Dopaminergic Enhancement of Learning and Memory in Healthy Adults and Patients With Dyslexia

Start date: January 2005
Phase: Phase 4
Study type: Interventional

This study aims to determine whether levodopa, in combination with a high frequency training of (grammatical) rules, is effective in boosting learning success in healthy subjects and whether this kind of training in combination with levodopa improves reading and spelling abilities of patients with dyslexia.