Periodontal Therapy on the Gut Microbiome of Inflammatory Bowel Disease

Status Recruiting

Clinical Trial Summary

Periodontitis and inflammatory bowel disease have been associated by meta-epidemiologic evidence, although their mechanistic connection needs to be further explored. Oral-gut axis is implicated in the pathogenesis of several chronic inflammatory conditions, but to date no studies have evaluated the impact of periodontal treatment on gut ecology. Thus, the present randomised clinical trial is aimed at investigating the effect of intensive or conventional periodontal therapy on the gut microbiome and parameters of systemic inflammation of patients diagnosed with inflammatory bowel disease.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04790825
Study type	Interventional
Source	University of Turin, Italy
Contact
Status	Recruiting
Phase	N/A
Start date	May 2, 2021
Completion date	May 15, 2023

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