Dupuytren's Disease Clinical Trial
Official title:
Registry of Dupuytren's Contracture Treatment Outcomes
Experience with Microbial Collagenase (trade name Xiapex) in Europe currently is limited to
randomised controlled studies.While such studies are essential to determine efficacy and
safety of the product (usually compared to placebo), they provide no information on the
effectiveness of the drug and further aspects of its use (feasibility, tolerability, quality
of life and other patient-related outcomes) in the typical "real-life" setting under
clinical practice conditions.Thus, the present study aims to collect data on the
- Drug utilization of Microbial Collagenase in the hand of physicians, with focus on
feasibility, treatment patterns, and effectiveness in clinical practice
- Context of Microbial Collagenase therapy (setting, patient characteristics, concomitant
treatment, follow-up therapy)
- Effectiveness (with focus on functionality)
- Tolerability
- Patient-related outcomes: patient satisfaction, health-related quality of life
- Physician satisfaction with therapy
- Resource utilization (hospital stays, drug consumption, concomitant medication etc.)
- Long-term outcomes
n/a
Observational Model: Cohort, Time Perspective: Prospective
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